Results 71 to 80 of about 23,848 (306)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PRE-HOSPITAL TREATMENT EFFECTIVENESS IN ATRIAL FIBRILLATION PAROXYSMS AMONG PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE

open access: yesРоссийский кардиологический журнал, 2010
The effectiveness of urgent medical care was retrospectively compared in 662 patients with atrial fibrillation (AF) paroxysms, arterial hypertension, and coronary heart disease; in addition, pre-hospital treatment tactics was evaluated.
V. G. Epifanov, V. T. Dolgikh
doaj  

Baccalaureate sermon [PDF]

open access: yes, 1991
Revelation 1:18; John 10 ...
Riekert, William E.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Creating and sustainable development of specialized centers as a way to improve quality of medical care

open access: yesБюллетень сибирской медицины, 2016
Quality of care is evaluated on the completeness of the survey, the correct diagnosis, treatment efficacy, and its duration. Improving the quality and efficiency of medical care for children with paroxysmal disorders of consciousness is one of topical ...
V. I. Guzeva   +4 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Benign Paroxysmal Torticollis

open access: yesLife
Background: The purpose of this review is to clarify the natural course of benign paroxysmal torticollis (BPT) and update the information on the relationship of this disorder with migraine. BPT belongs to a group of “episodic syndromes that may be associated with migraine” and is diagnosed according to diagnostic criteria of the International ...
Tozzi Elisabetta   +2 more
openaire   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

ROLE OF VIDEO-EEG OF MONITORING IN DIAGNOSTIC EPILEPTIC AND NOT EPILEPTIC PAROXYSMAL STATES AT CHILDREN

open access: yesЭпилепсия и пароксизмальные состояния, 2016
The purpose of examination was revealing diagnostic efficiency of video-EEG monitoring for children with paroxysms. 259 children are included in examination in the age from 1 month till 18 years, from which 103 (39,8 %) girls and 156 (60,2 %) boys.
V. I. Guzeva, O. V. Guzeva, V. V. Guzeva
doaj  

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