Results 81 to 90 of about 14,675 (263)
Кардиоваскулярная терапия и профилактика, 2006 Aim. To study prognostic value of high-resolution electrocardiography (HR-ECG), heart rate variability (HRV), QT interval dispersion and duration parameters, for assessing the risk of chronic heart failure (CHF) decompensation, atrial fibrillation (AF ...
A. E. Radzevich +3 more
doaj
Amiodarone-Induced Hypothyroidism
Кубанский научный медицинский вестник, 2019 Aim: to present a clinical case of amiodarone-induced hypothyroidism in a patient with paroxysmal atrial fi brillation.Results. Before taking amiodarone, the patient suffered from subclinical hypothyroidism. The level of thyroid stimulating hormone (TSH)
Svetlana A. Chepurnenko +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Epicrania fugax combining forward and backward paroxysms in the same patient: the first four cases
Journal of Pain Research, 2017 Johanna Barón-Sánchez,1 Álvaro Gutiérrez-Viedma,2 Marina Ruiz-Piñero,1 Alicia Pérez-Pérez,2 Ángel Luis Guerrero,1,3 María L Cuadrado2,4 1Headache Unit, Department of Neurology, Hospital Cl ...
Barón-Sánchez J +5 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Frontiers in Earth ScienceMount Etna is well known for its frequent lava fountains, or paroxysms, characterized by their intense explosive activity. Over the past decades, the Southeast Crater has been the most prolific, generating over a hundred events.
Alessandro Bonaccorso +3 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Heart Vessels and TransplantationObjective: To compare ablation outcomes and quality of life (QoL) of patients with typical atrial flutter (AFL) and concomitant atrial fibrillation (AF) paroxysms after cavotricuspid isthmus (CTI) ablation alone or combined with pulmonary vein isolation.
Anastasia Aker +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source