Results 91 to 100 of about 124,956,210 (348)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Dysarthric speech classification from coded telephone speech using glottal features

open access: yes, 2021
This paper proposes a new dysarthric speech classification method from coded telephone speech using glottal features. The proposed method utilizes glottal features, which are efficiently estimated from coded telephone speech using a recently proposed ...
Alku, Paavo   +1 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Chinese Text Readability Assessment Based on the Integration of Visualized Part-of-Speech Information with Linguistic Features

open access: yesAlgorithms
The assessment of Chinese text readability plays a significant role in Chinese language education. Due to the intrinsic differences between alphabetic languages and Chinese character representations, the readability assessment becomes more challenging in
Chi-Yi Hsieh   +5 more
doaj   +1 more source

Towards a Part-of-Speech Ontology

open access: yesNordic Journal of African Studies, 2012
This article describes the design of an electronic knowledge base, namely a morpho-syntactic database structured as an ontology of linguistic categories, containing linguistic units of two related languages of the South African Bantu group: Northern ...
Gertrud Faaß   +2 more
doaj   +1 more source

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