Results 71 to 80 of about 124,956,210 (348)

Automatic classification of vocal intensity category from speech

open access: yes, 2023
Regulation of vocal intensity is a fundamental phenomenon in speech communication. Vocal intensity can be quantified using sound pressure level (SPL), which can be measured easily by recording a standard calibration signal with speech and by comparing ...
Laaksonen, Laura   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Postfiltering with Complex Spectral Correlations for Speech and Audio Coding

open access: yes, 2018
State-of-the-art speech codecs achieve a good compromise between quality, bitrate and complexity. However, retaining performance outside the target bitrate range remains challenging.
Das, Sneha   +3 more
core   +1 more source

Wavelet-based adaptation of pitch contour to Lombard speech [PDF]

open access: yes, 2016
Peer ...
Suni, Antti Santeri   +5 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Analysis of Instantaneous Frequency Components of Speech Signals for Epoch Extraction

open access: yes, 2023
The major impulse-like excitation in the speech signal is due to abrupt closure of the vocal folds, which takes place at the glottal closure instant (GCI) or epoch in each cycle.
Alku, Paavo   +2 more
core   +1 more source

Towards the Construction of a Gold Standard Biomedical Corpus for the Romanian Language

open access: yesData, 2018
Gold standard corpora (GSCs) are essential for the supervised training and evaluation of systems that perform natural language processing (NLP) tasks. Currently, most of the resources used in biomedical NLP tasks are mainly in English.
Maria Mitrofan   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Morphological Analysis of the Slovak Language

open access: yesAdvances in Electrical and Electronic Engineering, 2015
This paper proposes a new statistic-based method of segmenting words by identification of a suffix. Ability to identify suffix can improve morphological analysis by allowing the classifier to assign tags to words previously unseen in the training corpus.
Daniel Hladek, Jan Stas, Josef Juhar
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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