Results 71 to 80 of about 26,645,245 (287)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Ateliers d'Anthropologie, 2019 Sparagmos and omophagia are considered imitations, even repetitions, of the killing of the Infant Dionysus. This article aims to show that the distinction between whole and part is an operator for the dismemberment of the Infant Dionysus and for its ...
Frédérique Ildefonse
doaj +1 more source
Jenna\u27s Story, Part I [PDF]
, 2010 In lieu of an abstract, below is the essay\u27s first paragraph. Jenna slid the needle into her pulsing brachial vein; she always used medical terms she had learned before she dropped out of school, at least the ones that she remembered from that long ...
Drey, Skye-Raven
core +1 more source
Directional Global Three-part Image Decomposition
, 2015 We consider the task of image decomposition and we introduce a new model coined directional global three-part decomposition (DG3PD) for solving it. As key ingredients of the DG3PD model, we introduce a discrete multi-directional total variation norm and ...
Gottschlich, Carsten, Thai, Duy Hoang
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Thinking, Experiencing and Rethinking Mereological Interdependence
Gestalt Theory, 2019 The present article is a partly ontological, partly Gestalt-psychological discussion of the thinkability of structures in which parts and whole are interdependent (MI). In the first section, I show that in the framework of E.
Stadler Michael W.
doaj +1 more source
The Form is Not a Proper Part in Aristotle’s Metaphysics Z.17, 1041b11–33
Metaphysics, 2018 When Aristotle argues at the 'Metaphysics' Z.17, 1041b11–33 that a whole, which is not a heap, contains ‘something else’, i.e. the form, besides the elements, it is not clear whether or not the form is a proper part of the whole.
Liva Rotkale
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source