Results 91 to 100 of about 511,149 (266)

Design and simulation of leg exoskeleton cycling-actuated wheelchair

open access: yesInternational Journal of Advanced Robotic Systems, 2017
This article presents a design of novel wheelchair with a leg exoskeleton for locomotion that can be powered by user legs through a cycling action. In addition, the control system is designed with leg-motion assistance for lower limb muscles to perform ...
Gao Huang   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Action at a Distance in Quantum Theory

open access: yesMathematics, 2015
The purpose of this paper is to present a consistent mathematical framework that shows how the EPR (Einstein. Podolsky, Rosen) phenomenon fits into our view of space time.
Jerome Blackman
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

New developments in the treatment of partial-onset epilepsy

open access: yesNeuropsychiatric Disease and Treatment, 2012
Frank MC Besag,1,2 Philip N Patsalos3,41South Essex Partnership University NHS Foundation Trust (SEPT), Mid Beds Clinic, Bedford, Bedfordshire, UK; 2Institute of Psychiatry, London, UK; 3Pharmacology and Therapeutics Unit, Department of Clinical and ...
Besag FM, Patsalos PN
doaj  

Transversal Shear Force in the Shear Connection of Twin-Girder Composite Bridges – Open vs. Semi-Closed Bridge Cross-Sections

open access: yesNordic Concrete Research
Steel-concrete composite bridges are commonly designed with full composite action between the steel girders and the concrete deck to enhance structural efficiency and durability.
Lic Victor Vestman,, Ivanov Stoyan
doaj   +1 more source

On the Equivalence of Elementary Surfaces with Respect to the Motion Group of Pseudo-Euclidean Space

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
This paper investigates the conditions for the equivalence of regular surfaces with respect to the action of a certain subgroup of linear transformations.
R.A. Gafforov, S. Kerbal, S.S. Juraboyev
doaj   +1 more source

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