Results 211 to 220 of about 186,836 (253)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

NatureKG: an ontology and knowledge graph for nature finance with a Text2Cypher application. [PDF]

Front Artif Intell
Kushwaha N, Singh A, Sheikh HA.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

PLM-Net: Perception Latency Mitigation Network for Vision-Based Lateral Control of Autonomous Vehicles. [PDF]

Sensors (Basel)
Khalil A, Kwon J.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Acute Effects of a Multi-Ingredient Preworkout Supplement on Peak Torque and Muscle Excitation During an Isokinetic Fatigue Protocol. [PDF]

Sports (Basel)
Connors BR, Camic CL, Jagim AR, Hill CM, Sebastião E, Chomentowski PJ, Kowal RA, de Leon MF.   +7 more
europepmc   +1 more source

Targeting disrupted networks in schizophrenia: Can muscarinic drugs make a fundamental difference? [PDF]

J Psychopharmacol
Pratt JA, Morris BJ.
europepmc   +1 more source

Pharmacological Insights into Optimal Dosing in Burning Mouth Syndrome: A Narrative Review of the Non-Linear Actions of Amitriptyline and Aripiprazole. [PDF]

J Clin Med
Nagamine T.
europepmc   +1 more source

Lean Six Sigma for Sharps Waste Management and Occupational Biosafety in Emergency Care Units. [PDF]

Int J Environ Res Public Health
Ayres MAC, Korzenowski AL, Dos Anjos FEV, Toigo T, Notarjacomo MHB.   +4 more
europepmc   +1 more source