Results 141 to 150 of about 448,559 (305)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

cDNA Cloning and Partial Characterization of the DJ-1 Gene from Tribolium castaneum. [PDF]

open access: yesAntioxidants (Basel), 2021
Sasaki S   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Characterization and performance evaluation of thermally treated black tea waste as partial fine aggregate replacement in concrete

open access: yesNext Sustainability
This study presents the characterization and performance evaluation of thermally treated black tea waste (BTW) as a partial replacement for fine aggregate (FA) in concrete. To assess its feasibility, raw BTW was incorporated at varying replacement levels
Md Helal Uddin Sarker   +5 more
doaj   +1 more source

Isolation, Partial Characterization and Application of Bacteriophages in Eradicating Biofilm Formation by Bacillus cereus on Stainless Steel Surfaces in Food Processing Facilities. [PDF]

open access: yesPathogens, 2022
Gdoura-Ben Amor M   +10 more
europepmc   +1 more source

Preparation and characterization of partial-cocrystallized catalyst-coated membrane for solid polymer electrolyte water electrolysis

open access: yes, 2013
A novel catalyst-coated membrane (CCM) for solid polymer electrolyte water electrolysis was fabricated by together crystallizing partial-crystallized Nafion membrane and catalyst layers.
Wang, Xunying   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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