Results 111 to 120 of about 1,497,624 (355)
Adjoint Methods for the Infinity Laplacian Partial Differential Equation
, 2011 To study fine properties of certain smooth approximations $${u^\varepsilon}$$ to a viscosity solution u of the infinity Laplacian partial differential equation (PDE), we introduce Green’s function $${\sigma^\varepsilon}$$ for the linearization.
L. Evans, Charles K. Smart
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Application of Partial Differential Equation Image Classification Methods to the Aesthetic Evaluation of Images [PDF]
, 2021 Feifeng Liu, Weihu Wang
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Software considerations for the “black box” solver FIDISOL for partial differential equations [PDF]
, 1987 Willi Schönauer, E. Schnepf
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Pan-American Journal of MathematicsThe method of lines (MOL) is a solution procedure for solving partial differential equation (PDE) and the Crank-Nicholson method (CNM) is an implicit finite difference method, used to solve the elliptic equation and similar partial differential equations
Md Roknujjaman +2 more
doaj +1 more source
An efficient quantum partial differential equation solver with chebyshev points. [PDF]
Sci Rep, 2023 Oz F, San O, Kara K.
europepmc +1 more source