Results 111 to 120 of about 1,441,473 (315)

Software for the numerical solution of first-order partial differential equations

open access: yesDiscrete and Continuous Models and Applied Computational Science, 2019
Partial differential equations of the first order, arising in applied problems of optics and optoelectronics, often contain coefficients that are not defined by a single analytical expression in the entire considered domain.
Yaroslav Yu Kuziv
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

ON SINGULAR SOLUTIONS OF CLAIRAUT EQUATIONS IN THE THEORY OF ORDINARY DIFFERENTIAL AND PARTIAL DERIVATIVE EQUATIONS

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. There is no problem in finding a general solution to the ordinary differential Clairaut equation. The corresponding procedure is described in details in the theory of ordinary differential equations.
L. A. Zhidova
doaj   +1 more source

Green's function of a centered partial difference equation

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2009
Applying a variation of Jacobi iteration we obtain the Green's function for the centered partial difference equation $$\Delta_{ww} u(x_{w-1},y_z) + \Delta_{zz} u(x_w,y_{z-1}) + f(u(x_w,y_z))=0,$$ which is the result of applying the finite difference ...
Richard Avery, Douglas Anderson
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Frequently Hypercyclic and Chaotic Behavior of Some First-Order Partial Differential Equation

open access: yesAbstract and Applied Analysis, 2013
We study a particular first-order partial differential equation which arisen from a biologic model. We found that the solution semigroup of this partial differential equation is a frequently hypercyclic semigroup.
Cheng-Hung Hung, Yu-Hsien Chang
doaj   +1 more source

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