Results 101 to 110 of about 3,715,842 (277)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Numerical Solution of Elliptic Partial Differential Equation: Method of Lines and Crank-Nicholson Method

Pan-American Journal of Mathematics
The method of lines (MOL) is a solution procedure for solving partial differential equation (PDE) and the Crank-Nicholson method (CNM) is an implicit finite difference method, used to solve the elliptic equation and similar partial differential equations
Md Roknujjaman, Mohammad Asif Arefin, Atish Kumar Joarder   +2 more
doaj   +1 more source

ON SINGULAR SOLUTIONS OF CLAIRAUT EQUATIONS IN THE THEORY OF ORDINARY DIFFERENTIAL AND PARTIAL DERIVATIVE EQUATIONS

Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. There is no problem in finding a general solution to the ordinary differential Clairaut equation. The corresponding procedure is described in details in the theory of ordinary differential equations.
L. A. Zhidova
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Solving Higher Orders Linear Complex Partial Differential Equations via Two Dimensional Differential Transform Method [PDF]

مجلة جامعة الانبار للعلوم الصرفة
Complex partial differential equation (CPDEs( appeared around the year 1900. D. Pompeiu was a famous mathematician who left a large impact in this field through introducing the Pompeiu integral operator, which forms a basis in the subject CDEs.
Amal Alhassan, Radhi Ali Zaboon, Shatha Alhily   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Frequently Hypercyclic and Chaotic Behavior of Some First-Order Partial Differential Equation

Abstract and Applied Analysis, 2013
We study a particular first-order partial differential equation which arisen from a biologic model. We found that the solution semigroup of this partial differential equation is a frequently hypercyclic semigroup.
Cheng-Hung Hung, Yu-Hsien Chang
doaj   +1 more source

Partial differential equations. An outline

Computers & Mathematics with Applications
This is a chart which may serve as an outline of classification, solution and examples for partial differential equations.
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

An efficient quantum partial differential equation solver with chebyshev points. [PDF]

Sci Rep, 2023
Oz F, San O, Kara K.
europepmc   +1 more source