Results 111 to 120 of about 3,715,842 (277)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

(Revised) The numerical solution of elliptic and parabolic partial differential equations with boundary singularities [PDF]

open access: yes, 1977
A general numerical method is described for the solution of linear elliptic and parabolic partial differential equations in the presence of boundary singularities.
Furzeland, RM, Crank, J
core   +2 more sources

An Efficient and Robust Partial Differential Equation Solver by Flash-Based Computing in Memory. [PDF]

open access: yesMicromachines (Basel), 2023
Qi Y   +10 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

On the Coalgebra of Partial Differential Equations.

open access: yes, 2019
We note that the coalgebra of formal power series in commutative variables is final in a certain subclass of coalgebras. Moreover, a system Sigma of polynomial PDEs, under a coherence condition, naturally induces such a coalgebra over differential polynomial expressions.
openaire   +4 more sources

A Partial Functional Differential Equation

open access: yesJournal of Mathematical Analysis and Applications, 2001
The author of this interesting paper investigates the partial functional differential equation \[ \partial u(x,t)\partial t =k \partial^2 u(x,t)\partial x^2+ru(x,t-T)[1-u(x,t)], \;\;t\geq 0, \;\;x\in [{}0,\pi ]{} \] under the boundary condition \(u(0,t)=u(\pi ,t)=0\) (\(t>0\)) and \(u(x,s)=\phi (x,s)\), \(-T\leq s\leq 0\), \(0\leq x\leq \pi \).
openaire   +2 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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