Results 171 to 180 of about 111,104 (316)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

An integrative phenotype-structured partial differential equation model for the population dynamics of epithelial-mesenchymal transition. [PDF]

NPJ Syst Biol Appl
Guilberteau J, Jain P, Jolly MK, Pouchol C, Pouradier Duteil N.   +4 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

A hybrid yang transform adomian decomposition method for solving time-fractional nonlinear partial differential equation. [PDF]

BMC Res Notes
Bekela AS, Deresse AT.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Central limit theorem and moderate deviations for a class of semilinear stochastic partial differential equations in any space dimension

D. N. Johnson, Leila Setayeshgar
openalex   +1 more source

Partial differential equation models for invasive species spread in the presence of spatial heterogeneity. [PDF]

PLoS One
Hughes EH, Moyers-Gonzalez M, Murray R, Wilson PL.   +3 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

A high-order solution to the characteristic initial value problem in hyperbolic partial differential equations [PDF]

, 1971
E. L. V. Hope
openalex   +1 more source

Retraction notice to "Exponential stability analysis of delayed partial differential equation systems: Applying the Lyapunov method and delay-dependent techniques" [Heliyon 10 (2024) e32650]. [PDF]

Heliyon
Tian H, Basem A, Kenjrawy HA, Al-Rubaye AH, Alfalahi STY, Azarinfar H, Khosravi M, Xia X.   +7 more
europepmc   +1 more source