Results 51 to 60 of about 3,715,842 (277)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Developmental Partial Differential Equations [PDF]

2015 54th IEEE Conference on Decision and Control (CDC), 2015
In this paper, we introduce the concept of Developmental Partial Differential Equation (DPDE), which consists of a Partial Differential Equation (PDE) on a time-varying manifold with complete coupling between the PDE and the manifold's evolution.
Pouradier Duteil, Nastassia, Rossi, Francesco, Boscain, Ugo, Piccoli, Benedetto   +3 more
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Classical and weak solutions of the partial differential equations associated with a class of two-point boundary value problems

Boundary Value Problems, 2018
This paper is concerned with a kind of first-order quasilinear parabolic partial differential equations associated with a class of ordinary differential equations with two-point boundary value problems. We prove that the function given by the solution of
Ning Ma, Zhen Wu
doaj   +1 more source

Studying a Tumor Growth Partial Differential Equation via the Black–Scholes Equation

Computation, 2020
Two equations are considered in this paper—the Black–Scholes equation and an equation that models the spatial dynamics of a brain tumor under some treatment regime. We shall call the latter equation the tumor equation.
Winter Sinkala, Tembinkosi F. Nkalashe
doaj   +1 more source

Differential transform method for conformable fractional partial differential equations [PDF]

Iranian Journal of Numerical Analysis and Optimization, 2019
We expand a new generalization of the two-dimensional differential trans form method. The new generalization is based on the two-dimensional differential transform method, fractional power series expansions, and conformable fractional derivative.
M. Eslami, S.A. Taleghani
doaj   +1 more source

Large deviations for stochastic Kuramoto–Sivashinsky equation with multiplicative noise

Nonlinear Analysis, 2021
The Kuramoto–Sivashinsky equation is a nonlinear parabolic partial differential equation, which describes the instability and turbulence of waves in chemical reactions and laminar flames. The aim of this work is to prove the large deviation principle for
Gregory Amali Paul Rose, Murugan Suvinthra, Krishnan Balachandran   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Existence and Uniqueness of the Solution of a Nonlinear Partial Differential Equation in the Eontinuous Functions of Holder and Sobolev Spaces

پژوهش‌های ریاضی, 2020
Introduction Complex analysis is a comparatively active branch in mathematics which has grown significantly. A deep look at the implications of continuity, derivative and integral in complex analysis and their relation with partial differential equations
Mozhgan Akbari, Fateme Joveini
doaj