Results 61 to 70 of about 879,634 (286)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

λ-Symmetry and μ-Symmetry Reductions and Invariant Solutions of Four Nonlinear Differential Equations

Mathematics, 2020
On one hand, we construct λ-symmetries and their corresponding integrating factors and invariant solutions for two kinds of ordinary differential equations.
Yu-Shan Bai, Jian-Ting Pei, Wen-Xiu Ma
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A Procedure to Construct Exact Solutions of Nonlinear Fractional Differential Equations

The Scientific World Journal, 2014
We use the fractional transformation to convert the nonlinear partial fractional differential equations with the nonlinear ordinary differential equations.
Özkan Güner, Adem C. Cevikel
doaj   +1 more source

Explicit Exact Solutions of the (2+1)-Dimensional Integro-Differential Jaulent–Miodek Evolution Equation Using the Reliable Methods

International Journal of Mathematics and Mathematical Sciences, 2020
In this article, we utilize the G′/G2-expansion method and the Jacobi elliptic equation method to analytically solve the (2 + 1)-dimensional integro-differential Jaulent–Miodek equation for exact solutions.
Supaporn Kaewta, Sekson Sirisubtawee, Nattawut Khansai   +2 more
doaj   +1 more source

Studying a Tumor Growth Partial Differential Equation via the Black–Scholes Equation

Computation, 2020
Two equations are considered in this paper—the Black–Scholes equation and an equation that models the spatial dynamics of a brain tumor under some treatment regime. We shall call the latter equation the tumor equation.
Winter Sinkala, Tembinkosi F. Nkalashe
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Monomiality and partial differential equations

Mathematical and Computer Modelling, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
G. Dattoli, GERMANO, Bruna, MARTINELLI, Maria Renata, RICCI, Paolo Emilio   +3 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

New solutions to a category of nonlinear PDEs

Frontiers in Physics
The nonlinear partial differential equations are not only used in many physical models, but also fundamentally applied in the field of nonlinear science. In order to solve certain nonlinear partial differential equation, the extended hyperbolic auxiliary
Bacui Li, Fuzhang Wang
doaj   +1 more source