Results 171 to 180 of about 42,017 (255)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

De Rerum Natura: How Do Halide Perovskites Self‐Heal From Damage?

open access: yesAdvanced Materials, EarlyView.
How can lead‐halide‐perovskites self‐heal after damage from light, heat, mechanical strain, or radiation? We show that reversible chemical defects underly performance losses and recovery, highlighting the roles of halide and proton migration, redox‐driven reactions, and acid‐base equilibria.
Davide Raffaele Ceratti   +2 more
wiley   +1 more source

Detection of hearing loss by formal audiological testing after acute infectious meningitis: a global systematic review and meta-analysis. [PDF]

open access: yesBMC Med
Alviz LF   +19 more
europepmc   +1 more source

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu   +8 more
wiley   +1 more source

2D MOF with Intrinsic Porosity for Colorimetric Volatile Organic Compounds (VOCs) Detection

open access: yesAdvanced Materials, EarlyView.
An uncommon 2D MOF with intrinsic in‐plane porosity that can be mechanically exfoliated undergoes a distinct and reversible colour change upon exposure to various volatile organic compounds. ABSTRACT In this work, we report an uncommon 2D metal–organic framework (MOF) with intrinsic in‐plane porosity that undergoes a distinct and reversible colour ...
Sergio R. Gamarra   +4 more
wiley   +1 more source

Positively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes

open access: yesAdvanced Materials, EarlyView.
A universal POPA strategy enables positively charged polymer‐brush MOFs with self‐adaptive interfacial interlocking to resist aggregation under fast processing. This design ensures seamless dispersion within large‐area selective layers, achieving 1 m‐wide roll‐to‐roll fabrication of pressure‐resistant MMCMs with tunable CO2 separation performance ...
Yi Yang   +11 more
wiley   +1 more source

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