Results 51 to 60 of about 214,445 (299)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Imaging time series for the classification of EMI discharge sources [PDF]
, 2018 In this work, we aim to classify a wider range of Electromagnetic Interference (EMI) discharge sources collected from new power plant sites across multiple assets. This engenders a more complex and challenging classification task.
Boreham, Philip +5 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Research of partial discharge detection for XLPE cable
Gong-kuang zidonghua, 2014 In order to extract characteristics of partial discharge signals, the paper proposed an adaptive threshold algorithm for processing partial discharge data by using ensemble empirical mode decomposition method for analysis of XLPE cable partial discharge ...
TANG Zhongyu +3 more
doaj +1 more source
Rough set theory applied to pattern recognition of partial discharge in noise affected cable data [PDF]
, 2016 This paper presents an effective, Rough Set (RS) based, pattern recognition method for rejecting interference signals and recognising Partial Discharge (PD) signals from different sources.
Hepburn, Donald M. +8 more
core +4 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
IEEE Access, 2019 The rapid growth of gas insulated switchgears as a compact, efficient, and reliable device has recently been given great attention. Albeit gas insulated switchgears can seldom suffer from failure due to the high resiliency and robustness, some severe ...
Ahmad Darwish +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A GIS Partial Discharge Defect Identification Method Based on YOLOv5
Applied Sciences, 2022 The correct identification of partial discharge types is of great significance to the stable operation of GIS. In order to improve the recognition accuracy and result of partial discharge, and to meet the requirements of real-time monitoring of GIS ...
Yao Lu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source