Results 71 to 80 of about 3,658,729 (281)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Vector Additive Decomposition for 2D Fractional Diffusion Equation

open access: yesNonlinear Analysis, 2008
Such physical processes as the diffusion in the environments with fractal geometry and the particles’ subdiffusion lead to the initial value problems for the nonlocal fractional order partial differential equations. These equations are the generalization 
N. Abrashina-Zhadaeva, N. Romanova
doaj   +1 more source

On global regularity of 2D generalized magnetohydrodynamic equations [PDF]

open access: yes, 2013
In this article we study the global regularity of 2D generalized magnetohydrodynamic equations (2D GMHD), in which the dissipation terms are –ν(–Δ)αu and –κ(–Δ)βb. We show that smooth solutions are global in the following three cases: α≥1/2, β≥1; 0≤α≤1/2,
Tran, Chuong Van   +2 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Matrix approach to discrete fractional calculus II: Partial fractional differential equations [PDF]

open access: yesJournal of Computational Physics, 2009
33 pages, 12 ...
Igor Podlubny   +4 more
openaire   +3 more sources

Efficient Caputo-based Solutions for Linear Time-Fractional Partial Differential Equations in Two and Three Dimensions

open access: yesJournal of Applied Science and Engineering
This study presents a new and highly efficient method for solving linear time-fractional partial differential equations (TFPDEs) in two and three dimensions. The proposed method utilizes Caputo fractional derivative to represent the time derivatives. The
Iman I. Gorial, Luma N. M. Tawfiq
doaj   +1 more source

Diffusive representations for fractional Laplacian: systems theory framework and numerical issues [PDF]

open access: yes, 2009
Bridging the gap between an abstract definition of pseudo-differential operators, such as (-\Delta)^{\gamma} for - 1/2 < \gamma < 1/2, and a concrete way to represent them has proved difficult; deriving stable numerical schemes for such operators is not ...
Matignon, Denis
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Global Stability for Fractional Diffusion Equations in Biological Systems

open access: yesComplexity, 2020
This paper proposes a new method of construction of Lyapunov functionals for the dynamical systems described by fractional differential equations and fractional partial differential equations. The proposed method is rigorously presented. Furthermore, the
Khalid Hattaf, Noura Yousfi
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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