Results 41 to 50 of about 6,741,041 (234)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Andrzej Lasota's selected results [PDF]

open access: yesOpuscula Mathematica, 2008
In this article we recall Andrzej Lasota's selected results which either indicated new directions of research, or layed the foundations for new approaches, or solved interesting problems. The area of mathematical interests of Professor Andrzej Lasota was
Józef Myjak
doaj  

Bivariate Chebyshev polynomials of the fifth kind for variable-order time-fractional partial integro-differential equations with weakly singular kernel

open access: yesAdvances in Difference Equations, 2021
The shifted Chebyshev polynomials of the fifth kind (SCPFK) and the collocation method are employed to achieve approximate solutions of a category of the functional equations, namely variable-order time-fractional weakly singular partial integro ...
Khadijeh Sadri   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

On solutions of several Fermat-type partial differential-difference equations in C2

open access: yesDemonstratio Mathematica
In this paper, we study entire solutions of several Fermat-type partial differential-difference equations in C2 ${\mathbb{C}}^{2}$ by applying Nevanlinna theory of meromorphic functions in several complex variables.
Tang Caoqiang, Huang Zhigang
doaj   +1 more source

Reduction of Linear Functional Systems using Fuhrmann's Equivalence

open access: yesSultan Qaboos University Journal for Science, 2016
Functional systems arise in the treatment of systems of partial differential equations, delay-differential equations, multidimensional equations, etc. The problem of reducing a linear functional system to a system containing fewer equations and unknowns ...
Mohamed S. Boudellioua
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Periodic solutions for some partial neutral functional differential equations

open access: yesElectronic Journal of Differential Equations, 2006
In this work, we study the existence of periodic solutions for partial neutral functional differential equation. We assume that the linear part is not necessarily densely defined and satisfies the Hille-Yosida condition.
Rachid Benkhalti   +2 more
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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