Results 61 to 70 of about 6,741,041 (234)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Measure functional differential equations and functional dynamic equations on time scales
, 2012 We study measure functional differential equations and clarify their relation to generalized ordinary differential equations. We show that functional dynamic equations on time scales represent a special case of measure functional differential equations ...
Mesquita, Jaqueline Godoy +5 more
core +1 more source
Optimal control of stochastic partial differential equations in Banach spaces [PDF]
, 2010 In this thesis we study optimal control problems in Banach spaces for stochastic partial differential equations. We investigate two different approaches.
Serrano Perdomo, Rafael Antonio
core +4 more sources
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Variation of constants formula for functional parabolic partial differential equations
Electronic Journal of Differential Equations, 2007 This paper presents a variation of constants formula for the system of functional parabolic partial differential equations $$displaylines{ frac{partial u(t,x)}{partial t} = DDelta u+Lu_t+f(t,x), quad t>0,; uin mathbb{R}^n cr frac{partial u(t,x ...
Hugo Leiva, Alexander Carrasco
doaj
Genetic programming approaches for solving elliptic partial differential equations
, 2008 In this paper, we propose a technique based on genetic programming (GP) for meshfree solution of elliptic partial differential equations. We employ the least-squares collocation principle to define an appropriate objective function, which is optimized ...
Sobester, A. +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
On functional differential equations associated to controlled structures with propagation
Electronic Journal of Qualitative Theory of Differential Equations, 2016 The method of integration along the characteristics has turned to be quite fruitful for qualitative analysis of physical and engineering systems described by large classes of partial differential equations of hyperbolic type in the plane (time and one ...
Vladimir Rasvan
doaj +1 more source
A survey of partial differential equations in geometric design [PDF]
, 2008 YesComputer aided geometric design is an area where the improvement of surface generation techniques is an everlasting demand since faster and more accurate geometric models are required.
Willis, P. +3 more
core +1 more source