Results 71 to 80 of about 1,401,079 (253)

Hospital Volume and Operative Mortality in Pancreaticoduodenectomy and Hepatectomy: Analysis of the National Clinical Database in Japan

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose This study evaluated the association between institutional advanced hepatobiliary‐pancreatic (HBP) surgical volume and operative mortality for pancreaticoduodenectomy (PD) and advanced hepatectomy using data from the Japanese National Clinical Database.
Yoshitaro Shindo, Hideki Endo, Hiroyuki Yamamoto, Hidenori Takahashi, Shigeru Marubashi, Atsushi Nanashima, Itaru Endo, Hideki Ueno, Ken Shirabe, Masafumi Nakamura, Hiroaki Nagano, Masayuki Ohtsuka   +11 more
wiley   +1 more source

Perioperative Risks of Concurrent Pancreatic and Hepatic Resections for Neuroendocrine Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Pancreatic neuroendocrine tumors (pNETs) account for 1%–2% of pancreatic tumors, with an increasing incidence. The safety of concurrent pancreas‐liver resections remains uncertain. This study evaluated the national outcomes of concurrent pancreatectomy and liver‐directed surgery for pNETs. Methods ACS‐NSQIP (2019–2023)
Amir Ebadinejad, Ashrita Raghuram, Sophia Xiao, Ethan Angle, Hassan Aziz   +4 more
wiley   +1 more source

SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models

JCI Insight, 2022
Disrupted liver regeneration following hepatectomy represents an “undruggable” clinical challenge associated with poor patient outcomes. Yes-associated protein (YAP), a transcriptional coactivator that is repressed by the Hippo pathway, is instrumental ...
Ryan D. Watkins, EeeLN H. Buckarma, Jennifer L. Tomlinson, Chantal E. McCabe, Jennifer A. Yonkus, Nathan W. Werneburg, Rachel L. Bayer, Patrick P. Starlinger, Keith D. Robertson, Chen Wang, Gregory J. Gores, Rory L. Smoot   +11 more
doaj   +1 more source

Predictive Value of Nutrition Indices in Advanced Hepatocellular Carcinoma Patients Treated With Lenvatinib

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI) are simple markers that reflect immune and nutritional status. This retrospective study evaluated their prognostic significance in 276 patients with advanced hepatocellular carcinoma (HCC) who received first‐line lenvatinib. PNI and GNRI were calculated based on
Cheng‐Wei Kuo, Wei‐Chen Tai, Yen‐Hao Chen, Ming‐Chao Tsai, Jing‐Houng Wang, Sheng‐Nan Lu, Tsung‐Hui Hu, Chao‐Hung Hung, Chien‐Hung Chen, Yuan‐Hung Kuo   +9 more
wiley   +1 more source

Changes of Branched Chain Amino Acids and Tyrosine Ratio (BTR) after Hepatectomy [PDF]

, 2003
To clarify the clinical usefulness of measuring branched chain amino acids and tyrosine ratio (BTR), which is correlated with Fischer's ratio, we examined the serum BTR level in 33 patients with liver diseases. Serum levels of branched-chain amino acids (
Nanashima, Atsushi, Sawai, Terumitsu, Morino, Shigeyuki, Yamaguchi, Hiroyuki, Shibasaki, Shinichi, Tsuji, Takashi, Abo, Takafumi, Tanaka, Kenji, Nakagoe, Tohru, Ayabe, Hiroyoshi, Yoshinaga, Megumi, Hidaka, Shigekazu   +11 more
core  

Control of rate and extent of the proliferative response after partial hepatectomy

, 1997
To examine the role of the early changes occurring in the liver within the first hours after a partial hepatectomy and in an attempt to demonstrate the involvement of subsequent regulatory mechanisms, the size of the remnant liver was modified at various
Luc Lambotte, Sandrine Triest, Triest, Sandrine, Tagliaferri, Eugenio M., Alain Saliez, Eugenio M. Tagliaferri, Andrew P. Barker, Lambotte, Luc, Barker, Andrew P., Baranski, Andrzej G., Andrzej G. Baranski, Saliez, Alain   +11 more
core   +1 more source

Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway

Redox Biology, 2018
Liver regeneration has important clinical importance in the setting of partial hepatectomy (PH). Following PH, quiescent hepatocytes can reenter cell cycle to restore liver mass.
Shibo Sun, Fang Xie, Xiaoping Xu, Qing Cai, Qifan Zhang, Zhonglin Cui, Yujian Zheng, Jie Zhou   +7 more
doaj   +1 more source

Isolation of primary human hepatocytes from partial hepatectomy specimens.

, 2012
Isolation of primary human hepatocytes from partial hepatectomy specimens.
Sang-Hoon Lee (38744), Yoon Young Choi (113840), Da Yoon No (113835), Ju Yun Jang (113846), DoYeun Park (113843), Dong-Sik Kim (113849), Seung-A Lee (113837)   +6 more
core   +1 more source

Interactive Roles of Metabolic Dysfunction‐Associated Steatotic Liver Disease and Nutritional Status in the Prognosis of Patients With Hepatocellular Carcinoma After Surgical Resection

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prognostic effect of concurrent metabolic dysfunction‐associated steatotic liver disease (MASLD) on outcomes for hepatocellular carcinoma (HCC) patients remains unclear. The Prognostic Nutritional Index (PNI) reflects nutritional and inflammatory status and is a well‐known prognostic factor.
Chun‐Ting Ho, Chien‐An Liu, Chia‐Jung Ho, Yi‐Chen Lin, Shin‐Yu Tsai, Hao‐Jan Lei, Shu‐Cheng Chou, Yi‐Hsiang Huang, Ming‐Chih Hou, Jaw‐Ching Wu, Chien‐Wei Su   +10 more
wiley   +1 more source

Partial hepatectomy induces delayed hepatocyte proliferation and normal liver regeneration in ovariectomized mice

, 2015
Makoto Umeda,1 Masaki Hiramoto,1,2 Takeshi Imai1 1Department of Aging Intervention, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; 2Department of Biochemistry, Tokyo Medical University, Tokyo, Japan Abstract: Estrogens play ...
Hiramoto M, Umeda M, Imai T
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