Results 51 to 60 of about 112,882 (301)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Rapid and Nondestructive Detection Method for Rapeseed Quality Using NIR Hyperspectral Imaging Spectroscopy and Chemometrics

Applied Sciences, 2023
In this study, a fast and non-destructive method was proposed to analyze rapeseed quality parameters with the help of NIR hyperspectral imaging spectroscopy and chemometrics. Hyperspectral images were acquired in the reflectance mode.
Du Wang, Xue Li, Fei Ma, Li Yu, Wen Zhang, Jun Jiang, Liangxiao Zhang, Peiwu Li   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Modified partial least square structural equation model with multivariate adaptive regression spline: Parameter estimation technique and applications

MethodsX
Partial Least Squares Structural Equation Modelling (PLS-SEM) struggles with nonlinear relationships between latent variables, leading to biased results.
Hendra H. Dukalang, Bambang Widjanarko Otok, Purhadi   +2 more
doaj   +1 more source

Partial least square regression versus domain invariant partial least square regression with application to near-infrared spectroscopy of fresh fruit

, 2020
Calibration models required for near-infrared (NIR) spectroscopy-based analysis of fresh fruit frequently fail to extrapolate adequately to conditions not encountered during initial data acquisition.
Mishra, Puneet, Nikzad-Langerodi, Ramin
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Tide modeling using partial least squares regression

, 2020
This research explores the novel use of the partial least squares regression (PLSR) as an alternative model to the conventional least squares (LS) model for modeling tide levels. The modeling is based on twenty tidal constituents: M2, S2, N2, K1, O1, MO3,
Ndehedehe, Christopher, Onuwa, Okwuashi, Attai, Hosanna   +2 more
core  

Human accelerated regions (HAR): Partial least square regression (PLSR) coefficients with multiple covariates.

, 2017
Human accelerated regions (HAR): Partial least square regression (PLSR) coefficients with multiple covariates.
Srdjan Djurovic (170173), Ingrid Melle (207704), Aree Witoelar (841516), David A. Collier (184865), Francesco Bettella (777081), Sahar Hassani (139319), Saurabh Srinivasan (3635974), Wesley K. Thompson (407291), Rahul S. Desikan (127522), Andrew J. Schork (407292), Yunpeng Wang (172933), Anders M. Dale (127526), Ole A. Andreassen (170286)   +12 more
core   +1 more source

Perbandingan Validasi Metode Partial Least Square Regression dan Jaringan Syaraf Tiruan dalam Memprediksi Curah Hujan Bulanan di Kabupaten Wajo, Sulawesi Selatan [PDF]

, 2021
Dari penelitian yang dilakukan dapat disimpulkan jika metode yang digunakan dalam memprediksi curah hujan lebih baik yaitu menggunakan metode Jaringan Syaraf Tiruan dibandingkan menggunakan metode Partial Least Square Regression.
Jusman, Nurfadhilah
core