Results 71 to 80 of about 876,733 (274)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Non-Metric Partial Least Squares
Electronic Journal of Statistics, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Use of Partial Least Squares Method To Remove Multicollinearity [PDF]
المجلة العراقية للعلوم الاحصائية, 2010 In this research the estimation of the regression parameters was clarified using least squares and partial least squares compared with the normal method in terms of its ability to be free from the problem of Multicollinearity between the predictive ...
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Partial Least Squares based algorithm for parsimonious variable selection
Algorithms for Molecular Biology, 2011 Background In genomics, a commonly encountered problem is to extract a subset of variables out of a large set of explanatory variables associated with one or several quantitative or qualitative response variables.
Mehmood Tahir +4 more
doaj +1 more source
Partial least squares for face hashing [PDF]
Neurocomputing, 2016 Face identification is an important research topic due to areas such as its application to surveillance, forensics and human-computer interaction. In the past few years, a myriad of methods for face identification has been proposed in the literature, with just a few among them focusing on scalability.
dos Santos, Cassio +3 more
openaire +1 more source
Systems Analysis by Partial Least Squares [PDF]
, 1983 This Collaborative Paper is one of a series embodying the outcome of a workshop and conference on Economic Structural Change: Analytical Issues, held at IIASA in July and August 1983.
Wold, H.
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Partial least squares for dependent data [PDF]
Biometrika, 2016 The partial least squares algorithm for dependent data realisations is considered. Consequences of ignoring the dependence for the algorithm performance are studied both theoretically and in simulations. It is shown that ignoring certain non-stationary dependence structures leads to inconsistent estimation.
Singer, M. +3 more
openaire +5 more sources