Results 81 to 90 of about 876,733 (274)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Optimization Method of Fusing Model Tree into Partial Least Squares
ITM Web of Conferences, 2017 Partial Least Square (PLS) can’t adapt to the characteristics of the data of many fields due to its own features multiple independent variables, multi-dependent variables and non-linear.
Yu Fang +5 more
doaj +1 more source
Partial Least Squares Regression on Symmetric Positive-Definite Matrices
Revista Colombiana de Estadística, 2013 Recientemente ha habido un aumento en el interés de analizar diferentes tipos de datos variedad-valuados, dentro de los cuáles aparecen los datos de matrices simétricas definidas positivas.
RAÚL ALBERTO PÉREZ +1 more
doaj
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Bin-3-Way-PARAFAC-PLS: A 3-Way Partial Least Squares for Binary Response
AxiomsIn various research domains, researchers frequently encounter multiple datasets pertaining to the same subjects, with one dataset providing explanatory variables for the others.
Elisa Frutos-Bernal +2 more
doaj +1 more source
Envelopes and Partial Least Squares Regression
Journal of the Royal Statistical Society Series B: Statistical Methodology, 2013 SummaryWe build connections between envelopes, a recently proposed context for efficient estimation in multivariate statistics, and multivariate partial least squares (PLS) regression. In particular, we establish an envelope as the nucleus of both univariate and multivariate PLS, which opens the door to pursuing the same goals as PLS but using ...
Cook, R. D., Helland, I. S., Su, Z.
openaire +1 more source
Partial least squares discriminant analysis: A dimensionality reduction method to classify hyperspectral data [PDF]
, 2018 The recent development of more sophisticated spectroscopic methods allows acquisition of high dimensional datasets from which valuable information may be extracted using multivariate statistical analyses, such as dimensionality reduction and automatic ...
Andrea, Bellincontro +2 more
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source