Results 51 to 60 of about 397,347 (283)
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter +17 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Estimating Outliers Using the Iterative Method in Partial Least Squares Regression Analysis for Linear Models. [PDF]
Outliers affect the accuracy of the estimated parameters of the partial least squares regression model and give unacceptably large residual values. Traditional robust methods (used in ordinary least squares) cannot be used to treat outliers in estimating
Mahammad Bazid, taha ali
doaj +1 more source
A medium-N approach to macroeconomic forecasting [PDF]
This paper considers methods for forecasting macroeconomic time series in a framework where the number of predictors, N, is too large to apply traditional regression models but not sufficiently large to resort to statistical inference based on double ...
Cubadda, G, Guardabascio, B
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Partial least squares regression (PLSR), spectral residual augmented classical least squares (SRACLS) and support vector regression (SVR) are three different chemometric models.
Ibrahim A. Naguib
doaj +1 more source
Partial Least Squares: A Versatile Tool for the Analysis of High-Dimensional Genomic Data [PDF]
Partial Least Squares (PLS) is a highly efficient statistical regression technique that is well suited for the analysis of high-dimensional genomic data.
Boulesteix, Anne-Laure +1 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Partial Sums of the Least Squares Residuals of Spatial Observations Sampled According to a Probability Measure [PDF]
A functional central limit theorem for a sequence of partial sums processes of the least squares residuals of a spatial linear regression model in which the observations are sampled according to a probability measure is established.
Somayasa, W. (Wayan)
core +2 more sources
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

