Results 231 to 240 of about 3,648,084 (297)

The accuracy of preoperative ultrasound use in primary flexor tendon repair: A systematic review. [PDF]

JPRAS Open
Ryan F, Sanjid SS, Puneh S, Garikai K, Muholan K, Dariush N, Afshin M.   +6 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Adrenal hemangioma: A rare incidental tumor managed with laparoscopic partial adrenalectomy. [PDF]

Urol Case Rep
Dadpour M, Ahmadi N, Najarian M, Irandoost N, Ranjbar A, Hadaegh F.   +5 more
europepmc   +1 more source

Real-world outcomes of talimogene laherparepvec as salvage therapy for advanced melanoma. [PDF]

J Immunother Cancer
Yamada MM, Chandrasekhar S, Gooley TA, Chen RE, Doolittle-Amieva C, Ansstas G, Bhatia S, Hall ET, Nghiem PT, Park SY, Chen DY.   +10 more
europepmc   +1 more source

refineDLC: An advanced post-processing pipeline for DeepLabCut outputs. [PDF]

Biol Methods Protoc
Klecel W, Rahael H, Brooks SA.
europepmc   +1 more source

An Approach to Design Adaptive Clinical Trials With Time-to-Event Outcomes Based on a General Bayesian Posterior Distribution. [PDF]

Stat Med
McGree JM, Overstall AM, Jones M, Mahar RK.   +3 more
europepmc   +1 more source

Low Failure Rates and Favorable Outcomes of Meniscal Repair With Concomitant Anterior Cruciate Ligament Primary Repair at Minimum 2-Year Follow-up. [PDF]

Orthop J Sports Med
Mueller MM, Monteleone TC, Hingsamer V, Conner-Rilk S, Goodhart GC, O'Brien RJ, van der List JP, DiFelice GS.   +7 more
europepmc   +1 more source