Results 41 to 50 of about 309,663 (301)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Beta Autoregressive Moving Average Model with the Aranda-Ordaz Link Function

open access: yesAxioms
In this work, we introduce an extension of the so-called beta autoregressive moving average (βARMA) models. βARMA models consider a linear dynamic structure for the conditional mean of a beta distributed variable. The conditional mean is connected to the
Carlos E. F. Manchini   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Development of a Partial Proportional Odds Model for Pedestrian Injury Severity at Intersections

open access: yesPromet (Zagreb), 2020
Pedestrian injury in crashes at intersections often results from complex interaction among various factors. The factor identification is a critical task for understanding the causes and improving the pedestrian safety.
Xi Lu   +3 more
doaj   +1 more source

Not just the motives – The mediating role of perceived health-related value when predicting likelihood of buying plant-based drinkable snacks

open access: yesFuture Foods, 2023
A conceptual model on predicting consumers’ likelihood of buying plant-based drinkable snacks through food choice motives and consumers’ perceived health-related value of drinkable snacks was developed and tested with a total of 3078 consumers from the ...
Kyösti Pennanen   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Partial likelihood analysis of spatio-temporal point process data [PDF]

open access: yes, 2010
We investigate the use of a partial likelihood for estimation of the parameters of interest in spatio-temporal point-process models. We identify an important distinction between spatially discrete and spatially continuous models.
Diggle, P, Abellana, R, Kaimi, I
core   +1 more source

A Probabilistic Approach to Seismic Diffraction Imaging

open access: yesLithosphere, 2021
We propose and demonstrate a probabilistic method for imaging seismic diffractions based on path-integral imaging. Our approach uses oriented velocity continuation to produce a set of slope-decomposed diffraction images over a range of plausible ...
Luke Decker, Sergey Fomel
doaj   +1 more source

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