Results 51 to 60 of about 1,292,486 (242)

Does a Delayed ACLR >6 Months Yield The Same Clinical Outcomes as an ACLR Performed Within 6 Months? Retrospective Cohort Studies

open access: yesOrthopaedic Journal of Sports Medicine
Objectives: The optimal timing to perform an anterior cruciate ligament reconstruction (ACLR) has still become a debatable topic. Previous studies have suggested that an ACLR performed after six months resulted in inferior outcomes.
Calvin Calvin, Ghuna Arioharjo Utoyo
doaj   +1 more source

Video Tracking Using Dual-Tree Wavelet Polar Matching and Rao-Blackwellised Particle Filter

open access: yesEURASIP Journal on Advances in Signal Processing, 2009
We describe a video tracking application using the dual-tree Polar Matching Algorithm. We develop the dynamical and observation models in a probabilistic setting and study the empirical probability distribution of the Polar Matching output.
Sze Kim Pang   +3 more
doaj   +1 more source

Comparison of Survival Estimation Methods in the Analysis of Breast Cancer Data

open access: yesAsian Pacific Journal of Cancer Care, 2022
Objective: In many epidemiological studies or clinical trials, Cox Proportional Hazard model is the most commonly used technique for the analysis of effects of covariates on survival time when time are continuous and ties are present.
Olubimpe M. Oladuti, Paul O. Olopha
doaj   +1 more source

Semiparametric Relative-risk Regression for Infectious Disease Data

open access: yes, 2012
This paper introduces semiparametric relative-risk regression models for infectious disease data based on contact intervals, where the contact interval from person i to person j is the time between the onset of infectiousness in i and infectious contact ...
Kenah, Eben
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Jointly interventional and observational data: estimation of interventional Markov equivalence classes of directed acyclic graphs

open access: yes, 2013
In many applications we have both observational and (randomized) interventional data. We propose a Gaussian likelihood framework for joint modeling of such different data-types, based on global parameters consisting of a directed acyclic graph (DAG) and ...
Bühlmann, Peter, Hauser, Alain
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: a retrospective observational cohort study

open access: yesFrontiers in Oncology
BackgroundThe association between objective imaging response and first line immune checkpoint inhibitor (ICI) therapy regimes in advanced melanoma remains uncharacterized in routine practice.MethodsWe conducted a multi-center retrospective cohort ...
Mehul Gupta   +13 more
doaj   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

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