Results 51 to 60 of about 301,324 (265)

Multi-omics network inference with a Gaussian copula model

BMC Bioinformatics
Background Inferring partial correlation networks is essential in systems biology to uncover direct interactions between biological entities. Traditional Gaussian graphical models rely on the assumption of normally distributed data; this assumption is ...
Ekaterina Tomilina, Gildas Mazo, Florence Jaffrézic   +2 more
doaj   +1 more source

Partial Likelihood and Estimating Equations

, 1997
Consider a regression model for discrete-time stochastic processes, with a (partially specified) model for the conditional distribution of the response given the covariate and the past observations. Suppose we also have some knowledge about how the parameter of interest affects the conditional distribution of the covariate given the past.
Greenwood, P., Wefelmeyer, W.
openaire   +2 more sources

Misperception of Body Weight After Childhood Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Misperception of body weight can negatively impact the weight management efforts of childhood cancer survivors (CCSs). Both being overweight or underweight are associated with chronic health conditions commonly observed in CCS; therefore, accurate weight perception is critical for reducing long‐term health risks.
Fabiën N. Belle, Tomáš Sláma, Eva Haegler‐Laube, Reto D. Kurmann, Gabriela M. Kuster, Christoph Saner, Eva Scheler, Yara Shoman, Christina Schindera   +8 more
wiley   +1 more source

Does a Delayed ACLR >6 Months Yield The Same Clinical Outcomes as an ACLR Performed Within 6 Months? Retrospective Cohort Studies

Orthopaedic Journal of Sports Medicine
Objectives: The optimal timing to perform an anterior cruciate ligament reconstruction (ACLR) has still become a debatable topic. Previous studies have suggested that an ACLR performed after six months resulted in inferior outcomes.
Calvin Calvin, Ghuna Arioharjo Utoyo
doaj   +1 more source

Comparative phylogenetic analysis of Dobrava-Belgrade virus L and S genetic segments isolated from an animal reservoir in Serbia [PDF]

Archives of Biological Sciences, 2014
The Dobrava-Belgrade virus (DOBV) is a member of the Bunyaviridae family, genus Hantavirus, possessing a single-stranded RNA genome consisting of three segments, designated L (large), M (medium) and S (small).
Nikolić Valentina, Stajković N., Stamenković Gorana, Cekanac R., Marušić P., Jovanović N., Krstić Milena, Mladenović J., Šiljić Marina, Gligić Ana, Stanojević Maja   +10 more
doaj   +1 more source

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source

Video Tracking Using Dual-Tree Wavelet Polar Matching and Rao-Blackwellised Particle Filter

EURASIP Journal on Advances in Signal Processing, 2009
We describe a video tracking application using the dual-tree Polar Matching Algorithm. We develop the dynamical and observation models in a probabilistic setting and study the empirical probability distribution of the Polar Matching output.
Sze Kim Pang, James D. B. Nelson, Simon J. Godsill, Nick Kingsbury   +3 more
doaj   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: a retrospective observational cohort study

Frontiers in Oncology
BackgroundThe association between objective imaging response and first line immune checkpoint inhibitor (ICI) therapy regimes in advanced melanoma remains uncharacterized in routine practice.MethodsWe conducted a multi-center retrospective cohort ...
Mehul Gupta, Mehul Gupta, Igor Stukalin, Igor Stukalin, Daniel E. Meyers, Daniel E. Meyers, Daniel Y. C. Heng, Daniel Y. C. Heng, Jose Monzon, Jose Monzon, Tina Cheng, Tina Cheng, Vishal Navani, Vishal Navani   +13 more
doaj   +1 more source