Results 91 to 100 of about 54,463 (287)

On the extension of partial metrics and quasi-metrics

open access: yesApplied General Topology
In a recent article, V. Mykhaylyuk and V. Myronyk investigated the problem of extending partial metrics and quasi-metrics. Concretely, they stated, and proved, as a main result that if A is a closed subset of a partially metrizable space (X,τ) then every
Salvador Romaguera, Pedro Tirado
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Matkowski's type theorems for generalized contractions on (ordered) partial metric spaces

open access: yesApplied General Topology, 2011
We obtain extensions of Matkowski's fixed point theorem for generalized contractions of Ciric's type on 0-complete partial metric spaces and on ordered 0-complete partial metric spaces, respectively.
Salvador Romaguera
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A Generalized Meir-Keeler-Type Contraction on Partial Metric Spaces

open access: yesAbstract and Applied Analysis, 2012
We introduce a generalization of the Meir-Keeler-type contractions, referred to as generalized Meir-Keeler-type contractions, over partial metric spaces.
Hassen Aydi   +2 more
doaj   +1 more source

Rational g-omega-weak contractions and fixed point theorems in 0-sigma-complete metric-like spaces

open access: yesNonlinear Analysis, 2017
We bring in the notion of rational g-ω-weak contractions in metric-like spaces and demonstrate common fixed point results for such mappings in 0-σ-complete metric-like spaces.
Hemant Kumar Nashine   +2 more
doaj   +1 more source

Partial S-metric spaces and coincidence points

open access: yesFilomat, 2019
In this paper, the concept partial S-metric space is introduced as a generalization of S-metric space. We prove certain coincidence point theorems in partial S-metric spaces. The results we obtain generalize many known results in fixed point theory. Also, some examples show the e_ectiveness of this approach.
Asil, M. Simkhah   +2 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A generalized contraction principle in partial metric spaces

open access: yesMathematical and Computer Modelling, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kieu Phuong Chi   +2 more
openaire   +1 more source

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