Results 51 to 60 of about 213,974 (315)

Abundant wave solutions of conformable space-time fractional order Fokas wave model arising in physical sciences

Alexandria Engineering Journal, 2021
The higher dimensional Fokas equation is the integrable expansion of the Kadomtsev-Petviashvili (KP) and Davey-Stewartson (DS) equations. The Fokas model has an important role in wave theory, to describe the physical phenomena of waves on the surface and
Shahzad Sarwar, Khaled M. Furati, Muhammad Arshad   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Second-order characterizations via partial smoothing [PDF]

, 2019
Smooth entropies are a tool for quantifying resource trade-offs in information theory and cryptography. However, in typical multi-partite problems some of the sub-systems are often left unchanged and this is not reflected by the standard smoothing of ...
Jain, Rahul, Mario Berta, Berta, Mario, Anurag Anshu, Rahul Jain, Berta, M, Tomamichel, Marco, Anshu, Anurag, Marco Tomamichel, Tomamichel, M, Anshu, A, Jain, R   +11 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Fixed Point Theorems on Nonlinear Binary Operator Equations with Applications

Discrete Dynamics in Nature and Society, 2014
The existence and uniqueness for solution of systems of some binary nonlinear operator equations are discussed by using cone and partial order theory and monotone iteration theory.
Baomin Qiao
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Measuring Structural Dissimilarity Between Finite Partial Orders [PDF]

, 2013
In this paper, we address the problem of measuring structural dissimilarity between two partial orders with n elements. We propose a structural dissimilarity measure, based on the distance between isomorphism classes of partial orders, and propose an ...
Arcagni A, Rosanna Grassi, Alberto Arcagni, Fattore M, Marco Fattore, Grassi R   +5 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Exploring partial order of European countries [PDF]

, 2009
Partial Order Theory has been recently more and more employed in applied science to overcome the intrinsic disadvantage hidden in aggregation, if a multiple attribute system is available.
R. Brüggemann, P. Annoni, Rainer Brüggemann, Paola Annoni   +3 more
core   +1 more source