Results 111 to 120 of about 1,017,520 (318)

Matrix partial orders through generalized inverses: unified theory

Linear Algebra and its Applications, 1991
Auf der Menge der \(m\times n\)-Matrizen über einem Körper sind verschiedene (teilweise) Ordnungen speziell mit Hilfe geeigneter Mengen verallgemeinerter Inversen definierbar. Verf. unterwirft derartige Definitionen einem einheitlichen Prinzip: Es sei \({\mathcal G}\) eine Abbildung, die jeder entsprechenden Matrix A eine Menge \({\mathcal G}(A ...
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Various Definitions of Multiple Differentiability of a Function f: ℝⁿ→ ℝ

Mathematics, 2020
Since the 17-th century the concepts of differentiability and multiple differentiability have become fundamental to mathematical analysis. By now we have the generally accepted definition of what a multiply differentiable function f:Rn→R is (in this ...
Alexander Kuleshov
doaj   +1 more source

Towards Patterns for Heaps and Imperative Lambdas

, 2015
In functional programming, point-free relation calculi have been fruitful for general theories of program construction, but for specific applications pointwise expressions can be more convenient and comprehensible.
Naumann, David A.
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

An automaton over data words that captures EMSO logic

, 2011
We develop a general framework for the specification and implementation of systems whose executions are words, or partial orders, over an infinite alphabet.
B. Bollig, Benedikt Bollig, Claire David, Daniel Brand, F. Neven, H. Björklund, L. Segoufin, M. Kaminski, M. Kaminski, M. Leucker, N. Tzevelekos, P. Bouyer, R. Alur, Stéphane Demri, T. Schwentick   +14 more
core   +2 more sources

Shadow Cones: Unveiling Partial Orders in Hyperbolic Space

arXiv.org, 2023
Tao Yu, Toni J.B. Liu, Albert Tseng, Chris De Sa   +3 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Impulse control problem on finite horizon with execution delay [PDF]

, 2007
We consider impulse control problems in finite horizon for diffusions with decision lag and execution delay. The new feature is that our general framework deals with the important case when several consecutive orders may be decided before the effective ...
Bruder, Benjamin, Pham, Huyen
core   +2 more sources