Results 41 to 50 of about 99,568 (264)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Relaxing Time Windows by Partial Orders in Routing Problems With Stacking Constraints

open access: yesIEEE Access, 2019
In vehicle routing problems, time windows are often used to formulate partial order relations between tasks in optimization model and related algorithm. However, time-window and partial order constraints are not equivalent.
Chen Wei, Zhi-Hua Hu, Wen-Wen Gao
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Global optimization using $\alpha$-ordered proximal contractions in metric spaces with partial orders

open access: yesApplied General Topology, 2016
The purpose of this article is to establish the global optimization with partial orders for the pair of non-self mappings, by introducing new type of contractions like $\alpha$-ordered contractions and $\alpha$-ordered proximal contraction in the frame ...
Somayya Komal, Poom Kumam
doaj   +1 more source

Partial Representations of Orderings [PDF]

open access: yesInternational Journal of Uncertainty, Fuzziness and Knowledge-Based Systems, 2018
In the present paper a new concept of representability is introduced, which can be applied to not total and also to intransitive relations (semiorders in particular). This idea tries to represent the orderings in the simplest manner, avoiding any unnecessary information.
G. Bosi, A. Estevan, M. Zuanon
openaire   +6 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Exact Solutions of the 3D Fractional Helmholtz Equation by Fractional Differential Transform Method

open access: yesJournal of Function Spaces, 2022
In this work, we applied the fractional reduced differential transform method (FRDTM) to find the exact solutions of the three-dimensional fractional Helmholtz equation (FHE) and compared our outcomes with the tenth-order approximate solutions for ...
Saleh Alshammari, Salah Abuasad
doaj   +1 more source

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