Results 111 to 120 of about 4,582,653 (258)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A new dynamic method for measuring hydrogen partial pressure in molten aluminum alloy [PDF]

China Foundry, 2011
Hydrogen partial pressure is an important parameter to calculate hydrogen concentration levels in molten aluminum alloy. A new dynamic method for measuring hydrogen partial pressure in molten aluminum alloy is studied.
Sun Qian, Li Dayong, Wang Lihua
doaj  

Thin film oxygen partial pressure sensor [PDF]

, 1972
The development is described of a laboratory model oxygen partial pressure sensor using a sputtered zinc oxide thin film. The film is operated at about 400 C through the use of a miniature silicon bar.
Honbarrier, H. L., Wortman, J. J., Harrison, J. W., Yen, J.   +3 more
core  

Partial pressure of carbon dioxide and methane in surface water around Spitsbergen in 1993

, 2003
Partial pressure of carbon dioxide and methane in surface water around Spitsbergen in ...
Ushio, Shuki, Shuki Ushio (7889471)
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Reverse water gas-shift reaction product driven dynamic activation of molybdenum nitride catalyst surface

Nature Communications
In heterogeneous catalysis catalyst activation is often observed during the reaction process, which is mostly attributed to the induction by reactants. In this work we report that surface structure of molybdenum nitride (MoN x ) catalyst exhibits a high ...
Hui Xin, Rongtan Li, Le Lin, Rentao Mu, Mingrun Li, Dan Li, Qiang Fu, Xinhe Bao   +7 more
doaj   +1 more source

Analysis of webs of partial-tension-field beams subjected to lateral pressure loadings [PDF]

, 1966
Webs of partial-tension-field beams subjected to lateral pressure ...
Nelson, L. A., Kovalevsky, L., Furuike, T., Rish, F. L.   +3 more
core  

CO₂ Partial Pressure at Different Time Points (Mean±SD, n = 21).

, 2014
Correlation between end-tidal carbon dioxide partial pressure (PetCO2) and arterial carbon dioxide partial pressure (PaCO2) and transcutaneous carbon dioxide partial pressure (PTCCO2) and PaCO2 at 4 time points ...
Yingying Yu (546494), Xing Chen (140292), Xuan Liu (49954), Cunming Liu (546495), Shijiang Liu (546493), Jie Sun (74648)   +5 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source