Results 81 to 90 of about 87,104 (294)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

A dummy peak elimination based MPPT technique for PV generation under partial shading condition

IET Renewable Power Generation, 2021
The increased energy demand with recent advancement in technology has led the global energy producers to move towards solar energy. Partial shading is a phenomenon that can severely affect the production of the solar power in the photovoltaic system ...
Boni Satya Varun Sai, Sarang A. Khadtare, Debashis Chatterjee   +2 more
doaj   +1 more source

A Novel Global MPP Tracking of Photovoltaic System Based on Whale Optimization Algorithm [PDF]

, 2016
To harvest maximum amount of solar energy and to attain higher efficiency, photovoltaic generation (PVG) systems are to be operated at their maximum power point (MPP) under both variable climatic and partial shaded condition (PSC).
Kumar, C. S. (Cherukuri), Rao, R. S. (Rayapudi)   +1 more
core   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

An efficient metaheuristic optimization algorithm for optimal power extraction from PV systems under various weather and load-changing conditions

Array
Currently, the focus has been shifted towards exploring solar energy due to its environmentally friendly and economic nature. However, the efficiency of photovoltaic (PV) systems can be impacted by factors such as ineffective Global Maxima (GM) tracking,
Md.Al Imran Fahim, Md.Salah Uddin Yusuf, Monira Islam, Munshi Jawad Ibne Azad   +3 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce, Goknur Selen Kocak, José Verdú‐Díaz, Jorge Alonso‐Pérez, Kristl G. Claeys, Tanya Stojkovic, Gorka Fernández‐Eulate, Pascal Laforêt, Najoua Miladi, Filipe Di Pace, Cristiane Araujo Martins Moreno, Edmar Zanoteli, Conrad C. Weihl, Volker Straub, Ana Töpf, Jordi Díaz‐Manera, Sarcoglycan European Cohort Consortium, Adele D′Amico, Adolfo López de Munain, Alicia Alonso‐Jiménez, Ana Camacho‐Salas, Andrea Gangfuß, Andrés Nascimento, Anna Sarkozy, Anneke J. van der Kooi, Arturo Fraga‐Bau, Béla Melegh, Benedikt Schoser, Bjarne Udd, Blaz Koritnik, Carlos Ortez, Chiara Marini Bettolo, Chiara Panicucci, Claudia Weiss, Claudio Bruno, Claudio Semplicini, Cristina Dominguez‐González, Cristina Garrido, David Gómez‐Andrés, Edoardo Malfatti, Elena Pegoraro, Elke De Vos, Francina Munell, Gabriele Dekomien, Giacomo Pietro Comi, Giorgio Tasca, Isabelle Richard, Jan L. De Bleecker, Jana Haberlová, Jesper Helbo Storgaard, Johanna Palmio, John Vissing, Juan Carlos de Leon‐Hernández, Kinga Hadzsiev, Laura Costa‐Comellas, Lea Leonardis, Leroy ten Dam, Lidia González‐Quereda, Luca Bello, Luisa Politano, Manuela Santos, Marianne de Visser, Marie Rohlenová, Matteo Garibaldi, Michela Guglieri, Nicolas Deconinck, Nicoline Løkken, Omar Abdel‐Mannan, Pia Gallano, Roberto Fernández‐Torrón, Ulrike Schara‐Schmidt, Vincenzo Nigro, Vittoria Zangaro   +72 more
wiley   +1 more source

Multicore PSO Operation for Maximum Power Point Tracking of a Distributed Photovoltaic System under Partially Shading Condition

International Journal of Photoenergy, 2016
This paper identifies the partial shading problem of a PV module using the one-diode model and simulating the characteristics exhibiting multiple-peak power output condition that is similar to a PV array.
Ru-Min Chao, Ahmad Nasirudin, I-Kai Wang, Po-Lung Chen   +3 more
doaj   +1 more source

Investigation of Zero-Sound Dispersion Equation in the Complex Plane of Frequency

, 2005
The known solutions to the zero-sound dispersion equation are considered as placed on the physical and unphysical sheets in the complex plane of frequency.Comment: 15 pages, 7 ...
A. B. Migdal, A. B. Migdal, A. L. Fetter, A. M. Dyugaev, C. Gale, C. J. Pethick, D. Pines, D.-O. Backman, E. G. Drukarev, E. Oset, G. E. Brown, G. E. Brown, G. Mao, I. Ya. Pomeranchuk, J. Diaz Alonso, J. Helgesson, J. Speth, L. B. Leinson, L. D. Landau, L. H. Xia, L. Liu, M. Colonna, M. F. M. Lutz, R. F. Sawyer, R. J. Furnstahl, T. Ericson, V. A. Sadovnikova, V. A. Sadovnikova, V. A. Sadovnikova, W. H. Dickhoff   +29 more
core   +3 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Feature Lines for Illustrating Medical Surface Models: Mathematical Background and Survey

, 2015
This paper provides a tutorial and survey for a specific kind of illustrative visualization technique: feature lines. We examine different feature line methods.
A. Chu, B. Preim, C. Hansen, D. DeCarlo, D. Eberly, D. Marr, E. Hameiri, E. Nadernejad, F. Ritter, J. Goldfeather, J. Zander, K. Hildebrandt, K. Hildebrandt, K. Lawonn, L. Zhang, L. Zhang, M. Burns, M.S. Floater, P. Alliez, P. Svetachov, S. Born, W. Kühnel, W.M. Jainek, X. Xie, Y. Ohtake   +24 more
core   +1 more source