Results 91 to 100 of about 5,293 (218)

Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viability [PDF]

, 2016
It was reported that prevention of acute portal overpressure in small-for-size livers by inflow modulation results in a better postoperative outcome. The aim is to investigate the impact of portal blood flow reduction by splenic artery ligation after ...
Abrantes, AM, Barbosa, JM, Botelho, MF, Campelos, S, Cardoso, D, Carrapita, J, Farges, O, Gonçalves, AC, Rocha, C, Santos, JN, Sarmento-Ribeiro, AB, Tralhão, JG   +11 more
core   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Very-Low-Dose Pegylated Interferon α2a Plus Ribavirin Therapy for Advanced Liver Cirrhosis Type C: A Possible Therapeutic Alternative without Splenic Intervention

Case Reports in Gastroenterology, 2010
Despite the recent progress in interferon (IFN) therapies for chronic hepatitis C, liver cirrhosis remains refractory. One of the major obstacles to successful IFN therapy is low platelet count.
Shogo Ohkoshi, Satoshi Yamagiwa, Masahiko Yano, Hiromichi Takahashi, Yo-hei Aoki, Yasunobu Matsuda, Yutaka Aoyagi   +6 more
doaj   +1 more source

Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes [PDF]

, 2017
C5 blockade by eculizumab prevents complement-mediated intravascular hemolysis in paroxysmal nocturnal hemoglobinuria (PNH). However, C3-bound PNH red blood cells (RBCs), arising in almost all treated patients, may undergo extravascular hemolysis ...
A Hill, A Hill, A Nicholson-Weller, A Roth, AM Risitano, AM Risitano, AM Risitano, AM Risitano, AM Risitano, Antonio M. Risitano, B Nilsson, CE Schoot van der, DJ Araten, DS Holt, E Lach-Trifilieff, E Marchiafava, G Gronowicz, GL Logue, GV Seaman, J Nishimura, J Takeda, JD Tamerius, JE May, JP Atkinson, JV Dacie, L Luzzatto, L Luzzatto, L Luzzatto, M Bessler, M Harboe, M Kono, M Loschi, M Sica, M Sica, MA Lindorfer, Maria De Angioletti, MH Holguin, Michela Sica, MJ Harder, MK Pangburn, MK Pangburn, P Hillmen, P Hillmen, P Hillmen, Patrizia Ricci, PJ Lachmann, PJ Lachmann, RJ Kelly, RL Sparrow, Rosario Notaro, RP Latour de, RP Rother, S Berentsen, SK Krishnan, T Olutogun, T Rondelli, TH Ham, Tommaso Rondelli, UM Reiss, VM Holers, VP Ferreira, WF Rosse, WF Rosse, Z Fishelson, Z Lin   +64 more
core   +2 more sources

Treatment of bleeding from a portion of pancreatojejunostomy after pancreaticoduodenectomy with division of the splenic vein: two case reports

Surgical Case Reports, 2019
Background There is no definitive strategy for gastrointestinal bleeding due to left-sided portal hypertension after pancreaticoduodenectomy (PD) for pancreatic cancer (PC) with concomitant portal vein resection (PVR). Case presentation Case 1: A 70-year-
Hiroki Kushiya, Takehiro Noji, Daisuke Abo, Takeshi Soyama, Kimitaka Tanaka, Yoshitsugu Nakanishi, Toshimichi Asano, Toru Nakamura, Takahiro Tsuchikawa, Keisuke Okamura, Satoshi Hirano   +10 more
doaj   +1 more source

Successful Treatment of Hypersplenism in Wilson's Disease by Partial Splenic Embolization

Journal of Investigative Surgery, 2018
Aim: Hypersplenism can occur in patients with Wilson's disease (WD). Surgical splenectomy is a conventional treatment for this condition; however, emotional and neurological deterioration may follow splenectomy.
Liang-Yong Li, Huai-Zhen Chen, Yuan-Cheng Bao, Qing-Sheng Yu, Wen-Ming Yang   +4 more
doaj   +1 more source

Thrombosis of a Superior Mesenteric Vein Aneurysm: Transarterial Thrombolysis and Transhepatic Aspiration Thrombectomy [PDF]

, 2018
We report the case of a 31-year-old woman presenting with abdominal pain due to acute thrombosis of a superior and inferior mesenteric vein aneurysm, which was treated by a combination of arterial thrombolysis and transhepatic thrombus aspiration. At the
Crook, D.W., Hechelhammer, L., Pfammatter, T., Widmer, U., Wildermuth, S.   +4 more
core  

CHOLESTEROL CRYSTAL EMBOLISM: A RECOGNIZABLE CAUSE OF RENAL DISEASE [PDF]

, 2000
7openopenFrancesco Scolari; Regina Tardanico; Roberta Zani; Alessandra Pola; Battista Fabio Viola; Ezio Movilli; Rosario MaiorcaScolari, Francesco; Regina, Tardanico; Roberta, Zani; Alessandra, Pola; Battista Fabio, Viola; Ezio, Movilli; Rosario ...
Alessandra Pola, Battista Fabio Viola, Ezio Movilli, Francesco Scolari, Regina Tardanico, Roberta Zani, Rosario Maiorca   +6 more
core   +1 more source

Severe gastric variceal haemorrhage due to splenic artery thrombosis and consecutive arterial bypass [PDF]

, 2011
Background Upper gastrointestinal haemorrhage is mainly caused by ulcers. Gastric varicosis due to portal hypertension can also be held responsible for upper gastrointestinal bleeding.
Klaus T von Trotha, Marcel Binnebösel, Son Truong, Florian F Behrendt, Hermann E Wasmuth, Ulf P Neumann, Marc Jansen   +6 more
core   +1 more source

Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials. [PDF]

, 2013
PurposePatients with advanced cholangiocarcinoma (CC) and gallbladder carcinoma (GC) have few therapeutic options for relapsed disease. methods: Given the overall poor prognosis in this population and the availability of novel targeted therapies, we ...
Falchook, Gerald S, Fu, Siqing, Hess, Kenneth R, Hong, David S, Janku, Filip, Javle, Milind, Kaseb, Ahmed O, Kurzrock, Razelle, Naing, Aung, Piha-Paul, Sarina, Subbiah, Ishwaria M, Subbiah, Vivek, Tsimberidou, Apostolia M, Wheler, Jennifer J, Wolff, Robert A   +14 more
core   +2 more sources