Results 1 to 10 of about 7,024 (148)

Effects of hypersplenism on the outcome of hepatectomy in hepatocellular carcinoma with hepatitis B virus related portal hypertension

Frontiers in Surgery, 2023
BackgroundAlthough hepatectomy plus splenectomy is not regularly recommended for hepatocellular carcinoma (HCC) with portal hypertension related hypersplenism due to the high risk accompanied with surgical procedures for now.
Rui Dong, Yanlong Cao, Jikai Yin
exaly   +3 more sources

Development and validation of a machine learning model for predicting hypersplenism in Wilson disease patients [PDF]

Frontiers in Medicine
ObjectiveWilson disease (WD) is a rare autosomal recessive copper metabolism disorder, with hypersplenism as a severe, common complication secondary to disease-related cirrhosis.
Qiaoyu Xuan, Xiuquan Shi, Xiuquan Shi, Lei Jin, Daiping Hua, Lanting Sun, Wenming Yang, Wenming Yang, Han Wang, Han Wang   +9 more
doaj   +2 more sources

Pancytopenia With Hypocellular Bone Marrow Revealing Extrahepatic Portal Venous Obstruction and Cavernous Transformation in a Child: A Case Report of a Diagnostic Challenge [PDF]

Clinical Case Reports
Extrahepatic portal venous obstruction (EHPVO) is a leading cause of prehepatic portal hypertension in children, particularly in developing countries.
Swekchha Adhikari, Aakash Pandit, Melisha Koirala, Biplav Lamichhane, Ram Khadka, Aashish Panta, Shuvra Rimal   +6 more
doaj   +2 more sources

Case Report: Refractory cold agglutinin disease with hypersplenism: efficacy of splenectomy in a patient treated with sutimlimab [PDF]

Frontiers in Immunology
Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia characterized by complement-mediated extravascular hemolysis. The introduction of complement inhibitors, particularly sutimlimab, has significantly improved disease control.
Antonella Sau, Daniela Onofrillo, Anna Caterina Russo, Gianfranco Di Prinzio, Anna Maria Quaglietta, Mauro Di Ianni, Mauro Di Ianni, Bruno Fattizzo, Bruno Fattizzo   +8 more
doaj   +2 more sources

Liver stiffness assessed by real-time two-dimensional shear wave elastography predicts hypersplenism in patients with Wilson’s disease: a prospective study

BMC Medical Imaging, 2022
Background The current study aimed to explore the value of liver stiffness assessed by two-dimensional real-time shear wave elastography (2D-SWE) to predict hypersplenism occurrence in Wilson’s disease (WD) patients.
Jiajia Wang, Minxia Hu, Qiang Zhu, Lanting Sun   +3 more
doaj   +1 more source

Sorafenib plus partial splenic embolism for treatment of hepatocellular carcinoma Barcelona stage C combined with hypersplenism: a case series

Journal of International Medical Research, 2021
Background Sorafenib is mainly used to treat patients with hepatocellular carcinoma (HCC) Barcelona Clinic Liver Cancer (BCLC) stage C, many of whom also have severe cirrhosis.
Jianting Zeng, Chunmei Wang, Yu Wang, Zhenhua Luo, Yanlin Zhang, Xianzhang Luo   +5 more
doaj   +1 more source

Efficacy and safety of laparoscopic splenectomy for hypersplenism secondary to portal hypertension after transjugular intrahepatic portosystemic shunt

BMC Gastroenterology, 2021
Background Laparoscopic splenectomy (LS) being used after Transjugular intrahepatic portosystemic shunt (TIPS) has not been reported. This report aims to explore the feasibility, safety, and potential efficacy of LS after TIPS hypersplenism secondary to ...
Yingying Li, Zuojin Liu, Chang’an Liu
doaj   +1 more source

Laparoscopic Splenectomy in Colorectal Cancer Patients with Chemotherapy-Associated Thrombocytopenia due to Hypersplenism

Case Reports in Oncology, 2012
Background: Hypersplenism due to chemotherapy-related liver injury has been associated with severe thrombocytopenia that may preclude continuation of systemic therapy for cancer patients. Patients treated for metastatic colorectal cancer (mCRC) are among
David A. Litvak, Salman Malad, Robert A. Wascher, Maurie Markman, Jiaxin Niu   +4 more
doaj   +1 more source

The protective effect of the spleen in sickle cell patients. A comparative study between patients with asplenia/hyposplenism and hypersplenism

Frontiers in Physiology, 2022
Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure.
Sari Peretz, Sari Peretz, Leonid Livshits, Leonid Livshits, Etheresia Pretorius, Asya Makhro, Anna Bogdanova, Anna Bogdanova, Max Gassmann, Ariel Koren, Carina Levin, Carina Levin   +11 more
doaj   +1 more source

An Uncommon Display of the Sickle Cell Trait Coupled with the Beta-Thalassemia Trait as Hypersplenism

Journal of Integrated Health Sciences, 2023
A structural flaw in the globin gene causes hemoglobinopathies, while a flaw in the globin chain’s synthesis causes thalassemia. One of the most prevalent hemoglobinopathies worldwide is sickle cell disease.
Divyesh Patel, Vedangi Desai, Palak Doshi, Shubham R. Darda, Jitendra D. Lakhani   +4 more
doaj   +1 more source