Results 1 to 10 of about 15,082 (235)

Liver stiffness assessed by real-time two-dimensional shear wave elastography predicts hypersplenism in patients with Wilson’s disease: a prospective study

BMC Medical Imaging, 2022
Background The current study aimed to explore the value of liver stiffness assessed by two-dimensional real-time shear wave elastography (2D-SWE) to predict hypersplenism occurrence in Wilson’s disease (WD) patients.
Jiajia Wang, Minxia Hu, Qiang Zhu, Lanting Sun   +3 more
doaj   +2 more sources

Efficacy and safety of laparoscopic splenectomy for hypersplenism secondary to portal hypertension after transjugular intrahepatic portosystemic shunt

BMC Gastroenterology, 2021
Background Laparoscopic splenectomy (LS) being used after Transjugular intrahepatic portosystemic shunt (TIPS) has not been reported. This report aims to explore the feasibility, safety, and potential efficacy of LS after TIPS hypersplenism secondary to ...
Yingying Li, Zuojin Liu, Chang’an Liu
doaj   +2 more sources

The protective effect of the spleen in sickle cell patients. A comparative study between patients with asplenia/hyposplenism and hypersplenism

Frontiers in Physiology, 2022
Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure.
Sari Peretz, Sari Peretz, Leonid Livshits, Leonid Livshits, Etheresia Pretorius, Asya Makhro, Anna Bogdanova, Anna Bogdanova, Max Gassmann, Ariel Koren, Carina Levin, Carina Levin   +11 more
doaj   +2 more sources

Clinical observation and risk assessment after splenectomy in hepatolenticular degeneration patients associated with hypersplenism

Frontiers in Surgery, 2022
BackgroundBoth hepatolenticular degeneration (HLD) and viral hepatitis B (HBV) can cause hypersplenism, but whether splenectomy is needed or can be performed in HLD patients associated with hypersplenism is still controversial.
Wanzong Zhang, Wanzong Zhang, Qingsheng Yu, Qingsheng Yu, Hui Peng, Hui Peng, Zhou Zheng, Zhou Zheng, Fuhai Zhou, Fuhai Zhou   +9 more
doaj   +2 more sources

Thalidomide for the Treatment of Thrombocytopenia and Hypersplenism in Patients With Cirrhosis or Thalassemia

Frontiers in Pharmacology, 2020
Hypersplenism and thrombocytopenia are common complications of liver cirrhosis or thalassemia, but current treatment strategies are limited. This study aimed to evaluate the efficacy and safety of thalidomide in the treatment of hypersplenism and ...
Yaocheng Chen, Ning Cai, Yongrong Lai, Weiwei Xu, Jinyan Li, Lan Huang, Ying Huang, Meiling Hu, Huangju Yang, Jiangming Chen   +9 more
doaj   +2 more sources

Effects of hypersplenism on the outcome of hepatectomy in hepatocellular carcinoma with hepatitis B virus related portal hypertension

Frontiers in Surgery, 2023
BackgroundAlthough hepatectomy plus splenectomy is not regularly recommended for hepatocellular carcinoma (HCC) with portal hypertension related hypersplenism due to the high risk accompanied with surgical procedures for now.
Jikai Yin, Xiao Chen
exaly   +3 more sources

Development and validation of a machine learning model for predicting hypersplenism in Wilson disease patients [PDF]

Frontiers in Medicine
ObjectiveWilson disease (WD) is a rare autosomal recessive copper metabolism disorder, with hypersplenism as a severe, common complication secondary to disease-related cirrhosis.
Qiaoyu Xuan, Xiuquan Shi, Xiuquan Shi, Lei Jin, Daiping Hua, Lanting Sun, Wenming Yang, Wenming Yang, Han Wang, Han Wang   +9 more
doaj   +2 more sources

Simultaneous CSM‐TACE with CalliSpheres® and partial splenic embolization using 8spheres® for hepatocellular carcinoma with hypersplenism: Early prospective multicenter clinical outcome

Frontiers in Oncology, 2022
BackgroundPrimary hepatocellular carcinoma is often complicated with hepatitis and liver cirrhosis. Some patients develop different degrees of splenomegaly, hypersplenism and hypohepatia due to the aggravation of liver cirrhosis, which to some extent ...
Jun Zhou, Jun Zhou, Zhuo Feng, Song Liu, Xiang Li, Ying Liu, Fei Gao, Jing Shen, Yue Wei Zhang, Guang Sheng Zhao, Ming Zhang   +10 more
doaj   +2 more sources

Successful Treatment of Hypersplenism in Wilson's Disease by Partial Splenic Embolization

Journal of Investigative Surgery, 2018
Aim: Hypersplenism can occur in patients with Wilson's disease (WD). Surgical splenectomy is a conventional treatment for this condition; however, emotional and neurological deterioration may follow splenectomy.
Liang-Yong Li, Huai-Zhen Chen, Yuan-Cheng Bao, Qing-Sheng Yu, Wen-Ming Yang   +4 more
doaj   +2 more sources

Case Report: Refractory cold agglutinin disease with hypersplenism: efficacy of splenectomy in a patient treated with sutimlimab [PDF]

Frontiers in Immunology
Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia characterized by complement-mediated extravascular hemolysis. The introduction of complement inhibitors, particularly sutimlimab, has significantly improved disease control.
Antonella Sau, Daniela Onofrillo, Anna Caterina Russo, Gianfranco Di Prinzio, Anna Maria Quaglietta, Mauro Di Ianni, Mauro Di Ianni, Bruno Fattizzo, Bruno Fattizzo   +8 more
doaj   +2 more sources