Results 11 to 20 of about 7,429 (165)

Pancytopenia With Hypocellular Bone Marrow Revealing Extrahepatic Portal Venous Obstruction and Cavernous Transformation in a Child: A Case Report of a Diagnostic Challenge [PDF]

Clinical Case Reports
Extrahepatic portal venous obstruction (EHPVO) is a leading cause of prehepatic portal hypertension in children, particularly in developing countries.
Swekchha Adhikari, Aakash Pandit, Melisha Koirala, Biplav Lamichhane, Ram Khadka, Aashish Panta, Shuvra Rimal   +6 more
doaj   +2 more sources

Development and validation of a machine learning model for predicting hypersplenism in Wilson disease patients [PDF]

Frontiers in Medicine
ObjectiveWilson disease (WD) is a rare autosomal recessive copper metabolism disorder, with hypersplenism as a severe, common complication secondary to disease-related cirrhosis.
Qiaoyu Xuan, Xiuquan Shi, Xiuquan Shi, Lei Jin, Daiping Hua, Lanting Sun, Wenming Yang, Wenming Yang, Han Wang, Han Wang   +9 more
doaj   +2 more sources

Laparoscopic Splenectomy for a Completely Infarcted Wandering Spleen After Prolonged Positional Abdominal Pain: A Case Report and Focused Literature Review [PDF]

Clin Case Rep
ABSTRACT A 19‐year‐old woman had a 7–8‐year history of positional abdominal pain, a mobile mass and transient thrombocytopenia. Computed tomography showed a completely infarcted wandering spleen with pedicle torsion. Fully laparoscopic splenectomy succeeded despite total infarction.
Awwad T, Jradi A, Deghaim R, Khalife M.
europepmc   +2 more sources

Case Report: Refractory cold agglutinin disease with hypersplenism: efficacy of splenectomy in a patient treated with sutimlimab [PDF]

Frontiers in Immunology
Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia characterized by complement-mediated extravascular hemolysis. The introduction of complement inhibitors, particularly sutimlimab, has significantly improved disease control.
Antonella Sau, Daniela Onofrillo, Anna Caterina Russo, Gianfranco Di Prinzio, Anna Maria Quaglietta, Mauro Di Ianni, Mauro Di Ianni, Bruno Fattizzo, Bruno Fattizzo   +8 more
doaj   +2 more sources

Splenectomy revisited in Wiskott–Aldrich syndrome in the era of HSCT and gene therapy: a bridge, a rescue, or simply obsolete? [PDF]

Frontiers in Immunology
Wiskott–Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency caused by mutations in the WAS gene, classically presenting with microthrombocytopenia, eczema, and recurrent infections, with an incidence of approximately 1 per 100, 000 live ...
Youssuf Khanafer, Ahmad Al-Naemi, Layan Khayyat, Farhan Cyprian   +3 more
doaj   +2 more sources

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Laparoscopic splenic artery ligation for hypersplenism in cirrhosis: A case series

Journal of Minimal Access Surgery, 2016
Background: Splenectomy for the treatment of hypersplenism in patients with cirrhosis (HIC) is related with complications. Laparoscopic splenic artery ligation (LSAL) may be an alternative treatment option.
Hirdaya H Nag, Sandip Chandrasekar, John M Manipadum, Bettageri G Vageesh   +3 more
doaj   +1 more source

Warren shunt combined with partial splenectomy in children with extra-hepatic portal hypertension, massive splenomegaly and severe hypersplenism [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Extra-hepatic portal vein obstruction (EHPVO) is one of the most often causes of portal hypertension in children. Objective. Establishing the importance of shunt surgery in combination with partial spleen resection in selected ...
Sretenović Aleksandar, Perišić Vojislav, Vujović Dragana, Opačić Dragan, Vukadinović Vojkan, Pavićević Polina, Radević Božina   +6 more
doaj   +1 more source

A rare case of primary follicular lymphoma of the spleen

Journal of Dr. NTR University of Health Sciences, 2016
Primary splenic lymphoma (PSL) is a rare entity accounting for less than 1% of lymphoid malignancies. Follicular lymphoma primarily involving the spleen is still rare and constitutes only 10% of the PSLs. PSLs constitute a heterogeneous group of diseases
Yerraguntla Subrahmanya Sarma, Manne Sriharibabu, Samir Ranjan Nayak, Kolluri Spoorthy   +3 more
doaj   +1 more source

Distal splenorenal shunt with partial spleen resection [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2007
Introduction: Hypersplenism is a common complication of portal hypertension. Cytopenia in hypersplenism is predominantly caused by splenomegaly. Distal splenorenal shunt (Warren) with partial spleen resection is an original surgical technique that ...
Gajin Predrag, Radević Božina, Nenezić Dragoslav, Ilijevski Nenad, Ješić-Vukićević Rada, Radak Đorđe   +5 more
doaj   +1 more source