Results 51 to 60 of about 3,425 (169)
Background The administration of direct-acting antiviral agents in patients with liver cirrhosis and hepatitis C has been shown to improve liver function and long-term prognosis after sustained virological response (SVR) is achieved. However, in patients
Ryoga Hamura +8 more
doaj +1 more source
Kaposiform hemangioendothelioma: Diagnosis and treatment
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian +5 more
wiley +1 more source
CN‐TIPS is a nationwide, multicenter prospective registry that will enroll 10,000 adults with portal hypertension undergoing transjugular intrahepatic portosystemic shunt in China, integrating perioperative clinical and hemodynamic metrics with standardized imaging (including computational modeling in a dedicated subcohort) and multi‐omics biospecimens,
Yi Xiang +20 more
wiley +1 more source
Thrombocytopenia is common in hepatocellular carcinoma and may increase bleeding risk during antiangiogenic therapy, yet the clinically relevant platelet threshold remains uncertain. We found that a baseline platelet count < 50 × 109/L was associated with bleeding; patients below this cutoff had a substantially higher bleeding rate than those with ...
Jun Tie +8 more
wiley +1 more source
Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang +6 more
wiley +1 more source
Variceal hemorrhage may cause high rebleeding and mortality rates. Preventing the first episode of variceal bleeding is mandatory in patients with high-risk esophageal varices (EV).
Tsuyoshi Ishikawa +8 more
doaj +1 more source
Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun +6 more
wiley +1 more source
Partial splenic embolization in a patient with SLE.
γ部分的脾動脈塞栓術(partial splenic embolization; PSE)を施行した著明な血小板減少を伴う全身性エリテマトーデス(SLE)の1例を報告する.患者は30歳女性でplatelet associated IgG (PAIgG)およびLupus anticoagulant (LAC)陽性のSLEでsteroid療法を施行していたが, steroid剤の減量とともに血小板数が著しく減少し, 1.0×4/μl以下となった.このため, betamethasone 50 mg/日3日間のセミパルス療法, γ-globulin大量療法を3回ずつ施行したが一時的な効果しか得られなかった.脾摘術を行うには危険性が高いためPSEを施行した.
Maehiro, Kouhei +3 more
openaire +2 more sources
Guidelines for Essential Trauma Care: Second Edition (2026)
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock +41 more
wiley +1 more source
Background The spleen is also the largest lymphoid organ and has important immune and haematopoietic functions. Traumatic splenic rupture often results in haemorrhagic shock and is life-threatening.
Xiaolong Xu +3 more
doaj +1 more source

