Results 111 to 120 of about 1,455,811 (291)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Partial sums of starlike harmonic multivalent functions

open access: yes, 2015
In this paper, we study the ratio of starlike harmonic multivalent functions to its sequences of partial ...
Yalçın, Sibel, Yaşar, Elif
core   +1 more source

On the estimation of the convergence rate in the multidimentional limit theorem for the sum of weakly dependent random variables functions

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2018
A refinement of estimates of the convergence rate obtained earlier in the multidimensional central limit theorem for the sums of vectors generated by the sequences of random variables with mixing is close to optimal. This has been achieved by imposing an
F.G. Gabbasov   +2 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Norm and Numerical Radius Inequalities for Sums of Bounded Linear Operators in Hilbert Spaces [PDF]

open access: yes, 2006
Some inequalities for the operator norm and numerical radius of sums of bounded linear operators in Hilbert spaces are given.
Dragomir, Sever S
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Results on Generalized Logarithmic Mean and Beta-Logarithmic Function of Matrix Arguments

open access: yesJournal of Mathematics
The main focus of this manuscript is to provide generalizations of logarithmic mean and extended beta function in the framework of matrix setting.
Hala Abd Elmageed, Mohamed Abdalla
doaj   +1 more source

An Improved Version of the Parameterized Hardy–Hilbert Inequality Involving Two Partial Sums

open access: yesMathematics
In this paper, by employing the Euler–Maclaurin summation formula and real analysis techniques, an improved version of the parameterized Hardy–Hilbert inequality involving two partial sums is established.
Bicheng Yang, Shanhe Wu
doaj   +1 more source

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