Results 51 to 60 of about 516,043 (283)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Partially coherent matter wave and its evolution

, 2007
The evolution and propagation of a partially coherent matter wave (PCMW) is investigated theoretically by the correlation function method. The ABCD matrix formalism previously used for a fully coherent matter wave is extended to the PCMW domain.
Anderson, Berman, Bongs, Dalfovo, Fujita, Goldstein, Griffin, Jun Chen, Ketterle, Lin, Mandel, Meystre, Miller, Morinaga, Naraschewski, Qiang Lin, Rusch, Schellekens, Taylor, Van Vleck, Viana Gomes, Wang, Zaremba   +22 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Partially-coherent waves with binominal coherence

, 2022
Comprehensive analysis of non-diffracting optical waves with binominal two-point coherence function (BCF) is presented. This coherence function consist of two terms, each depending on either separation of points or central point. We established the necessary and sufficient conditions for non-negative definiteness of the binominal coherence functions ...
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Second-Order Statistics of Self-Splitting Structured Beams in Oceanic Turbulence

Photonics, 2023
Free-space optical communication is restricted by random media-stimulated beam degradation. However, partially coherent structured beams modulated by the coherence structure can potentially mitigate this negative effect. By employing the extended Huygens–
Liming Liu, Yulu Liu, Hao Chang, Jifei Huang, Xinlei Zhu, Yangjian Cai, Jiayi Yu   +6 more
doaj   +1 more source

Filamentational Instability of Partially Coherent Femtosecond Optical Pulses in Air

, 2006
The filamentational instability of spatially broadband femtosecond optical pulses in air is investigated by means of a kinetic wave equation for spatially incoherent photons.
Bergé, Braun, Couairon, Couairon, Hall, Ivleva, Kato, Koenig, Korobkin, Lange, M. Marklund, Mlejnek, Mlejnek, Moh, Moyal, Nibbering, P. K. Shukla, Skarka, Skupin, Vinçotte, Wigner, Xi   +21 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Review on vortex beams with low spatial coherence

Advances in Physics: X, 2019
Vortex beams with helical phase, carrying phase singularity and orbital angular momentum, have attract great attention in the past decades due to their wide applications in optical communications, optical manipulation, super-resolution imaging and so on.
Xianlong Liu, Jun Zeng, Yangjian Cai
doaj   +1 more source