Results 51 to 60 of about 6,090,423 (307)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

An Observer-Based View of Euclidean Geometry

open access: yesMathematics
An influence network of events is a view of the universe based on events that may be related to one another via influence. The network of events forms a partially ordered set which, when quantified consistently via a technique called chain projection ...
Newshaw Bahreyni   +2 more
doaj   +1 more source

On Best Proximity Point Theorems without Ordering

open access: yesAbstract and Applied Analysis, 2014
Recently, Basha (2013) addressed a problem that amalgamates approximation and optimization in the setting of a partially ordered set that is endowed with a metric.
A. P. Farajzadeh   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Order-Sensitive Domination in Partially Ordered Sets and Graphs [PDF]

open access: yes, 2022
For a (finite) partially ordered set (poset) P, we call a dominating set D in the comparability graph of P, an order-sensitive dominating set in P if either x is an element of D or else a = 2, we associate to G a graded poset P-k(G) of height k, and ...
Mehmet Akif Yetim   +5 more
core   +1 more source

Fixed Point Theorems of Set-Valued Mappings in Partially Ordered Hausdorff Topological Spaces

open access: yesAbstract and Applied Analysis, 2014
In this work, several fixed point theorems of set-valued monotone mappings and set-valued Caristi-type mappings are proved in partially ordered Hausdorff topological spaces, which indeed extend and improve many recent results in the setting of metric ...
Shujun Jiang, Zhilong Li, Shihua Luo
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The morphology of partially ordered sets

open access: yesJournal of Combinatorial Theory, Series A, 1974
DEFINITION. XC gn is called a set of incomparable elements if A, B E X and A C B imply A = B. Then Sperner’s Theorem -maxx / X 1 = (,J,,), where X ranges over all sets of incomparable elements in .?3,, . The standard proof of Sperner’s theorem (see Harper-Rota [lo]) is based upon two properties of an , unimodality and matching.
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Coincidence points principle for set-valued mappings in partially ordered spaces

open access: yes, 2020
In the paper the concept of covering (regularity) for set-valued mappings in partially ordered spaces is introduced. The coincidence points problem for set-valued mappings in partially ordered spaces is considered. Sufficient conditions for the existence
Zhukovskiy S.E.   +2 more
core   +2 more sources

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