Results 51 to 60 of about 682,797 (231)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Ramsey numbers of partial order graphs (comparability graphs) and implications in ring theory

open access: yesOpen Mathematics, 2020
For a partially ordered set (A,≤)(A,\le ), let GA{G}_{A} be the simple, undirected graph with vertex set A such that two vertices a≠b∈Aa\ne b\in A are adjacent if either a≤ba\le b or b≤ab\le a.
Badawi Ayman, Rissner Roswitha
doaj   +1 more source

Liquid Crystal Phases of Quantum Hall Systems

open access: yes, 1998
Mean-field calculations for the two dimensional electron gas (2DEG) in a large magnetic field with a partially filled Landau level with index $N\geq 2$ consistently yield ``stripe-ordered'' charge-density wave ground-states, for much the same reason that
A. P. Young   +22 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A technique of tripled coincidence points for solving a system of nonlinear integral equations in POCML spaces

open access: yesJournal of Inequalities and Applications, 2020
This manuscript aims to initiate some recent theoretical consequences related to tripled coincidence points for non-self mappings via the notion of C-type functions in partially ordered complete metric-like space (for short, POCML space).
Hasanen A. Hammad, Manuel De La Sen
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Key Assignment Scheme with Authenticated Encryption

open access: yesIACR Transactions on Symmetric Cryptology, 2018
The Key Assignment Scheme (KAS) is a well-studied cryptographic primitive used for hierarchical access control (HAC) in a multilevel organisation where the classes of people with higher privileges can access files of those with lower ones.
Suyash Kandele, Souradyuti Paul
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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