Results 71 to 80 of about 6,955,994 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Sequential convergences on free lattice ordered groups [PDF]
, 1971 summary:In this paper the partially ordered set Conv $G$ of all sequential convergences on $G$ is investigated, where $G$ is either a free lattice ordered group or a free abelian lattice ordered ...
Jakubík, Ján, Paul F. Conrad
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Between quantum logic and concurrency [PDF]
Electronic Proceedings in Theoretical Computer Science, 2014 We start from two closure operators defined on the elements of a special kind of partially ordered sets, called causal nets. Causal nets are used to model histories of concurrent processes, recording occurrences of local states and of events. If every
Luca Bernardinello +2 more
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On the dimension of partially ordered sets
Discrete Mathematics, 1981 AbstractWe study the topic of the title in some detail. The main results are summarized in the first four paragraphs of this paper.
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
π1(K)-GRADED C ∗-ALGEBRAS GENERATED BY PARTIALLY ORDERED SET
, 2020 131-135В работе строится C ∗-алгебра над частично-упорядоченным множеством, в каж- дой точке которого задано гильбертово пространство. Доказывается, что эта ал- гебра является градуированной по 1-й гомотопической фундаментальной группе дан- ного частично-
Григорян С.А. +2 more
core
Journal of Inequalities and Applications, 2020 This manuscript aims to initiate some recent theoretical consequences related to tripled coincidence points for non-self mappings via the notion of C-type functions in partially ordered complete metric-like space (for short, POCML space).
Hasanen A. Hammad, Manuel De La Sen
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Graphical partially ordered sets
Discrete Applied Mathematics, 1987 The main results of this paper can be found in a generalization of reconstruction properties to a large class of combinatorial structures by a concept of g-graph. For example in the section 3, the author shows many results about the reconstruction conjecture: many of them are known for graphs, but author's proof generalizes them for digraphs ...
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