Results 91 to 100 of about 6,090,423 (307)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The 0-1 inverse maximum stable set problem [PDF]

open access: yes
Given an instance of a weighted combinatorial optimization problem and its feasible solution, the usual inverse problem is to modify as little as possible (with respect to a fixed norm) the given weight system to make the giiven feasible solution optimal.
Yerim Chung, Marc Demange
core  

Leveled partially ordered sets

open access: yesComputational and Applied Mathematics
Abstract This article presents our approach to modeling a problem posed by a company aiming to optimize the 3D printing of an object within the context of additive manufacturing, where each object is created layer by layer. We introduce the concept of leveled partially ordered sets to manage large sets of points that represent each layer of ...
Fernando Fueyo   +5 more
openaire   +5 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Generation of Permutations of a Partially Ordered Set with Element Dependencies Taken into Account

open access: yesСовременные информационные технологии и IT-образование
This paper is devoted to the development of methods that make it possible to substantially reduce the number of linear orders required for the analysis of partially ordered sets.
Ilya Andreev, Konstantin Vladimirov
doaj   +1 more source

A remark on the extension of the concept of incidence algebras to nonlocally finite partially ordered sets

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2004
An incidence algebra of a nonlocally finite partially ordered set Q is a very rare concept, perhaps nonexistent. In this note, we will attempt to construct such an algebra.
Boniface I. Eke
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Products of partially ordered quasigroups [PDF]

open access: yes, 1970
summary:We describe necessary and sufficient conditions for a direct product and a lexicographic product of partially ordered quasigroups to be a positive quasigroup.
Demko, Milan, Evans, Trevor
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Completion of partially ordered sets [PDF]

open access: yes, 2006
The paper considers a generalization of the standard completion of a partially ordered set through the collection of all its lower ...
Solovyov, Sergey
core   +1 more source

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