Results 91 to 100 of about 45,393 (304)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
P-Faithful Partially Ordered Sets
Доведено теорему, що описує P-точні впорядковані множини.We prove a theorem that describes P-faithful partially ordered ...
Сапелкин, А.И.
core +1 more source
A class of partially ordered sets: II
Hemion G. A class of partially ordered sets: II. Chaos, Solitons & Fractals. 1998;9(7):1219-1232.In a previous paper, a certain class of discrete partially ordered sets was defined and a number of general properties of the sets was described.
Geoffrey Hemion, Hemion, Geoffrey
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Evolutionary Search under Partially Ordered Fitness Sets [PDF]
The search for minimal elements in partially ordered sets is a generalization of the task of finding Pareto-optimal elements in multi-criteria optimization problems.
Rudolph, Günter
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Total compactness of a-inductive partially ordered sets [PDF]
A poset (i.e., partially ordered set) P is called A-inductive iff every nonempty well ordered subset W of P has a supremum (i.e., least upper bound) wich need not be an element of ...
Abian, Alexander, Kemp, Paula A.
core
The greedy algorithm for partially ordered sets
Those independence systems on finite partially ordered sets are characterized for which the greedy algorithm always ...
Ulrich Faigle, Faigle, Ulrich
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source

