Results 71 to 80 of about 45,393 (304)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Algorithmics of Posets Generated by Words Over Partially Commutative Alphabets (Extended) [PDF]

open access: yesScientific Annals of Computer Science, 2013
It is natural to try to relate partially ordered sets (posets in short) and classes of equivalent words over partially commutative alphabets. Their common graphical representation are Hasse diagrams.
Ł. Mikulski   +2 more
doaj   +1 more source

On the dimension of partially ordered sets

open access: yesDiscrete Mathematics, 1981
AbstractWe study the topic of the title in some detail. The main results are summarized in the first four paragraphs of this paper.
openaire   +1 more source

Completion of partially ordered sets

open access: yes, 2006
The paper considers a generalization of the standard completion of a partially ordered set through the collection of all its lower ...
Solovyov, Sergey
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Investigating Skew Derivations on Partially Ordered Sets: A Generalized Approach

open access: yesJournal of Mathematics
The main goal of this article is to discuss skew derivations on posets under certain criteria, some of which are novel. Moreover, a few examples illustrate that various restrictions forced within the framework of these results’ assumptions cannot be ...
Ahmed Abdelwanis   +3 more
doaj   +1 more source

Positive Solutions for a Class of Singular Boundary Value Problems with Fractional q-Difference Equations

open access: yesJournal of Function Spaces, 2015
We discuss a class of singular boundary value problems of fractional q-difference equations. Some existence and uniqueness results are obtained by a fixed point theorem in partially ordered sets. Finally, we give an example to illustrate the results.
Jufang Wang, Changlong Yu, Yanping Guo
doaj   +1 more source

Coupled Fixed Point Theorem for the Generalized Langevin Equation with Four-Point and Strip Conditions

open access: yesAdvances in Mathematical Physics, 2022
By considering a metric space with partially ordered sets, we employ the coupled fixed point type to scrutinize the uniqueness theory for the Langevin equation that included two generalized orders.
Ahmed Salem, Noorah Mshary
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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