Results 131 to 140 of about 45,393 (304)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

A Tutte Polynomial for Partially Ordered Sets

open access: yesJournal of Combinatorial Theory, Series B, 1993
We investigate the Tutte polynomial of a greedoid associated to a partially ordered set. In this case, we explore the deletion-contraction formula in two ways and develop an antichain expansion for the polynomial. We show that the polynomial can determine the number of order ideals, order filters and antichains of all sizes of a poset \(P\), but ...
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Efficient Reordering of Multiple Memory Operations in a Multithreaded Program

open access: yesСовременные информационные технологии и IT-образование
This paper is devoted to various methods of constructing all kinds of linear orders for partially ordered sets. The complexity of the problem lies in the fact that even for a set of small size, constructing and checking for any feature of its possible ...
Ilya Andreev, Konstantin Vladimirov
doaj   +1 more source

Metrics on partially ordered sets—A survey

open access: yesDiscrete Mathematics, 1981
AbstractWe review more or less recent results on metrics associated with valuations or (and) minimum weighted paths in posets, metric characterizations of posets and we point out some applications of these results to problems involving uses of distances in social sciences.
openaire   +1 more source

On a fixed point theorem for partially ordered sets

open access: yes, 1979
An elementary combinatorial proof is presented of the following fixed point theorem: Let P be a finite partially ordered set with a cut-set X. If every subset of X has either a meet or a join, then P has the fixed point property.
Paul H. Edelman, Edelman, Paul H.
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Partially Ordered Sets Associated with Permutations

open access: yesEuropean Journal of Combinatorics, 1989
Let \(\Sigma\) be a set of permutations of \([n]=\{1,...,n\}\). A poset P is called chain-permutational with respect to \(\Sigma\) iff the edges of the Hasse diagram of P can be labeled with labels from [n] so that the sequence of labels along each maximal chain of P is a permutation in \(\Sigma\), each permutation in \(\Sigma\) arises exactly once in ...
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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