Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He +9 more
wiley +1 more source
Impacts of national volume-based procurement policy on insulin price, volume and expenditure in China: a quasi-experimental study. [PDF]
Yi H, Tan S, Cai M, Kuai L, Xu D, Han S.
europepmc +1 more source
Polymorph‐Specific Electronic Transduction in WO3 during Molecular Sensing
Metal‐oxide polymorphs with similar surface chemistry can nevertheless exhibit distinct sensing properties. In γ‐ and ε‐WO3, analyte adsorption appears comparable; yet, only ε‐WO3 induces a pronounced lattice electronic perturbation that accommodates charge in sub‐conduction band minimum states.
Matteo D'Andria +6 more
wiley +1 more source
Efficacy and safety of switching to iGlarLixi from premixed insulin therapy in patients with type 2 diabetes: A real-world experience. [PDF]
Huang CJ +5 more
europepmc +1 more source
The particle with high surface hydrophilicity exhibits strong thermophoretic attraction, as its dense hydration layer enhances the role of interfacial water molecules in determining thermophoretic mobility over other ionic effects. This finding elucidates the mechanism underlying the robust thermophoretic accumulation of Escherichia coli in high ...
Seungyeop Kang +3 more
wiley +1 more source
Clinical and radiographic evaluation of premixed versus powder/liquid bioceramic mineral trioxide aggregate in indirect pulp capping of immature permanent mandibular molars: a randomized clinical trial. [PDF]
Khairy AM, Nasr RAT, Ali MM.
europepmc +1 more source
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza +11 more
wiley +1 more source
Sealing ability and marginal adaptation of premixed versus manually mixed bioceramic root-end filling materials: a systematic review and meta-analysis. [PDF]
Hattab A, Al-Tayyan M, Hajeer O.
europepmc +1 more source
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu +16 more
wiley +1 more source
The Effects of Three Modified Whole-Grain Corn Flours on the Quality of European-Style Bread. [PDF]
Tianying S, Zhuohao W, Jian R.
europepmc +1 more source

