Results 151 to 160 of about 6,488 (253)

Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2791-2802, August 2026.
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao, Bayan Nasr, J. Michael Köhler, Sebastian Buchinger   +3 more
wiley   +1 more source

Premixed insulin: Advantages, disadvantages, and future. [PDF]

World J Diabetes
Xia Y, Hu Y, Ma JH.
europepmc   +1 more source

Contrasting Effects of HT‐2 Toxin Exposure and ZIP6 Knockdown on Chondrocyte Extracellular Matrix Metabolism

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
HT‐2 toxin triggers chondrocyte damage and matrix metabolism disorders in KBD via suppressing ZIP6. ZIP6 knockdown alleviates these dysfunctions through FoxO, cAMP and TNF pathways, clarifying the molecular mechanism of cartilage injury. ABSTRACT Kashin‐Beck disease (KBD) is a chronic, endemic osteoarticular disorder associated with T‐2 toxin exposure,
Yang Liu, Yu Zhang, Ruitian Huang, Lulu Bai, Lian Liu, Chaowei Wang, Yirong Qin, Hui Wang, Xiong Guo, Xi Wang, Yujie Ning   +10 more
wiley   +1 more source

Effect of Ultrasonic Condensation Time on Void Formation and Microhardness of Well-Root^TM PT Apical Plugs in 3D-Printed Immature Teeth. [PDF]

Materials (Basel)
Hristov K, Bogovska-Gigova R.
europepmc   +1 more source

UV‐Assisted Direct Ink Writing of Fully Bio‐Derived Photopolymer Composites With High Cellulose Loadings

Macromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
Fully bio‐based, cellulose‐reinforced inks are developed to 3D print structures via UV‐assisted extrusion. The inks flow easily during printing and solidify rapidly under light, enabling stable shapes and improved performance. Post‐print treatment allows tuning of strength and stiffness, demonstrating a sustainable route toward functional, plant‐based ...
Maksims Jurinovs, Anda Gromova, Davis Veidmanis, Madara Veseta, Sabīne Greivule, Krisjanis Smits, Tobias Robert, Sergejs Gaidukovs   +7 more
wiley   +1 more source

Short-term dentin-pulp complex repair with four pulp capping materials: a double-blind randomized crossover histological study. [PDF]

Sci Rep
Muhamad A, Muhamad A, Lazkani T, Manadili A, Alsayed Tolibah Y.   +4 more
europepmc   +1 more source

Loss of Rab8a‐Dependent Tethering of Lipid Droplets to Mitochondria Contributes to Hypoxia–Reoxygenation Injury

MedComm, Volume 7, Issue 8, August 2026.
Rab8a‐dependent tethering of lipid droplets to mitochondria sustains fatty acid oxidation and cardiomyocyte metabolic flexibility under normoxia. During hypoxia/reoxygenation, Rab8a loss and PLIN5‐associated lipophagy uncouple lipid breakdown from mitochondrial utilization, driving lipotoxicity and cell death.
Jialing Tang, Nathan Joyce, Thomas Laval, Eddie Tam, Hye Kyoung Sung, Mireille Ouimet, Gary Sweeney   +6 more
wiley   +1 more source

Physicochemical Characterization of a Strontium Silicate-Based Root Canal Sealer Compared with Two Conventional Sealers. [PDF]

J Funct Biomater
Alsofi L.
europepmc   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Physics-encoded machine learning for performance and emission prediction of nickel ferrite nanocatalyst and hydrogen-enriched biodiesel in diesel engines. [PDF]

RSC Adv
Van Minh N, Jayabal R, Leo G M L, S S, L K, Joseph R, P J, Sivanraju R.   +7 more
europepmc   +1 more source