Results 141 to 150 of about 1,686,472 (316)
YouthIn the late 1970s, adolescents in East Harlem, New York, participated in a program called the Youth Action Program where they worked collectively to address systemic issues causing inequities in their communities (e.g., inequities in housing and ...
Elena Maker Castro +3 more
doaj +1 more source
Oral history interview with Participant 02
, 2017 Participant 2 shares their experiences utilizing and volunteering at food banks across Payne County, Oklahoma. They describe the sense of community that they feel in being able to volunteer and give back to the community of Stillwater and talk about how ...
Participant 02
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
'You Don't Know How Lucky You Are to Be Here!': Reflections on Covert Practices in an Overt Participant Observation Study [PDF]
There has been a tendency in sociology to see covert and overt roles of social researchers in participant observation studies as opposites. This is both in terms of the researcher role and the surrounding ethics, with the overt researcher role being seen
John S. McKenzie
core
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
PARTICIPANT-GENERATED IMPLEMENTATION INTENTIONS: INTERVENTION FIDELITY AND EFFICACY
, 2014 PARTICIPANT-GENERATED IMPLEMENTATION INTENTIONS: INTERVENTION FIDELITY AND ...
E Kothe (13719172), V Tan (13653943)
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source