Results 161 to 170 of about 1,686,472 (316)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Communication Experiences of Patients With Hearing Loss During Hemodialysis Treatment and the Potential Role of Communication Tools: A Qualitative Study. [PDF]

Can J Kidney Health Dis
DeBusschere A, Lunney M, Reid S, Verdin N, Love S, Crysdale G, Thompson S, Nicholas D, Boulton T, Schick-Makaroff K, Jenstad L, Straus S, Holroyd-Leduc J, Donald M, Sullivan PJ, Howarth T, Evans J, Tonelli M.   +17 more
europepmc   +1 more source

Participant-level differences between the highest values obtained in the cardiopulmonary exercise test (CPET) and verification phase for the seven studies where these data were available.

Participant-level differences between the highest values obtained in the cardiopulmonary exercise test (CPET) and verification phase for the seven studies where these data were available.
Sean Carroll (1723798), Victor A. B. Costa (10156616), Todd A. Astorino (10024084), Gustavo Z. Schaun (18271752), Felipe A. Cunha (10156622), Adrian W. Midgley (7239479), Julia K. Baumgart (5477927), Guilherme F. Fonseca (18271755)   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Home Visits by Mother-Child Nurses to Concerned Mothers and Infants in Japan: Characteristics of Mothers and Infants Who Receive Continued Support. [PDF]

Kobe J Med Sci
Kawashita N, Shiomi M, Ikeda R, Nomachi S, Okazaki Y, Yamamoto A, Izumi H.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Beyond the patient: how providers perceive and experience non-medical barriers in gastrointestinal cancer care. [PDF]

Support Care Cancer
Lal T, Moody D, Chiratanagandla R, Meehan G, Davey CH, Bora S, Stange K, Hoehn RS.   +7 more
europepmc   +1 more source

Les Archives de la parole : 1911-1913 / Aulard, Pasteur Emile Roberty, Paul Deschanel... [et al.], aut. ; Aulard, Pasteur Emile Roberty, Paul Deschanel... [et al.], participants

, 1911
Comprend : Histoire de la révolution à l'heure actuelle / Aulard, aut., participant ; Vers l'évangile social / Pasteur Emile Roberty, aut., participant ; Fragment d'un discours prononcé à la chambre des députés le 16 décembre 1911 sur l'accord franco ...
Baudin, Pierre (1863-1917). Auteur du texte, Deschanel, Paul (1855-1922). Auteur du texte, Roberty, Emile. Auteur du texte, Lintilhac, Eugène (1854-1920). Auteur du texte, Fournière, Joseph (1857-1914). Auteur du texte, Aulard, François-Alphonse (1849-1928). Auteur du texte, Sangnier, Marc (1873-1950). Auteur du texte, Vandervelde, Émile (1866-1938). Auteur du texte, Pottecher, Maurice (1867-1960). Auteur du texte, Déroulède, Paul (1846-1914). Auteur du texte, Dreyfus, Alfred (1859-1935). Auteur du texte, Pottecher, Camille. Auteur du texte, Messimy, Adolphe (1869-1935). Auteur du texte, Prévost, Marcel (1862-1941). Auteur du texte   +13 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Understanding Opportunity Costs of Women Participating in Maternal and Child Nutrition Interventions in Southern Angola: Evidence From the MuCCUA Trial. [PDF]

Matern Child Nutr
Martin-Cañavate R, Pujol-de Castro A, Puett C, Trigo E, de Lourdes Faria M, Gerardo AS, Vargas A, Molina I, Custodio E.   +8 more
europepmc   +1 more source