FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
What is the attitude towards and the current practice of information exchange during self-medication counselling in German community pharmacies? An assessment through self-report and non-participant observation. [PDF]
PLoS One, 2020 Seiberth JM +4 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Participant observation approach to study refugees’ information practices
Informaatiotutkimus, 2020 Khadijah Saeed Khan
doaj +1 more source
Conducting an Unplanned Participant Observation: The Case of a Non-Birder in Bird Watchers' Land
Forum: Qualitative Social Research, 2016 This article describes two participant observations of birdwatchers, which occurred by serendipity. Characteristics of personal and interpersonal behavior patterns are identified and illustrated.
Roni Berger
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Electronic Security Systems in Academic Libraries: A Case Study of Three University Libraries in South-West Nigeria. [PDF]
, 2011 This study examines the effectiveness of electronic security systems in academic libraries with a focus on selected university libraries in South-West Nigeria.
Osayande, Odaro
core +1 more source
Perceber a diferença: a observação participante enquanto metodologia na investigação sócio-espacial
Cidades, Comunidades e TerritórioThis essay aims to discuss how it is possible to work with the perception of axes of differentiation in contexts of socio-spatial research, contributing to the construction of the field of Urban Planning, which has experienced constant epistemological ...
Gabriel Barth da Silva, Júlia Silveira
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A Prisoners\u27 Island: Teaching Australian Incarcerated Students in the Digital Age [PDF]
, 2014 While incarcerated students have always faced many obstacles to full and effective participation in university study, the global shift toward paperless e-learning environments has created new challenges for prisoners without direct internet access. Based
Farley, Helen, Hopkins, Susan
core +1 more source